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Data were collected through self\u2010reported questionnaires. The questionnaire includes information about demographic, cancer characteristics, comorbidities, lifestyle factors, and sexual satisfaction. Sexual satisfaction was measured by a single\u2010item scale. The distribution of sexual satisfaction among different demographic and cancer characteristics was compared using the chi\u2010squared test. Logistic regression models were conducted to assess the effects of lifestyle factors, comorbidities on sexual satisfaction after adjustment for demographic and cancer characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>More than 40% of male and female cancer survivors reported no sexual satisfaction. Sexual satisfaction of cancer survivors is significantly associated with both the number and the type of comorbidities. Heart disease, musculoskeletal system disease, diabetes, and hyperlipidemia are the comorbidities significantly associated with sexual satisfaction of cancer survivors. Lifestyle factors other than smoking, including exercise or fitness, drinking alcohol, and eating fruits and vegetables are significantly correlated with sexual satisfaction. Besides, all of the above associations show gender differences. In addition, demographic characteristics include sex, age, marital status, living status, and average monthly income are also significantly associated with sexual satisfaction of cancer survivors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Comorbidity and lifestyle factors are associated with sexual satisfaction of cancer survivors, and the associations show gender differences. Improving the lifestyles of cancer survivors, and controlling and reducing their comorbidities are important for improving their sexual satisfaction.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.4118","type":"journal-article","created":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T07:26:43Z","timestamp":1626161203000},"page":"6058-6069","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Comorbidity, lifestyle factors, and sexual satisfaction among Chinese cancer survivors"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2527-6121","authenticated-orcid":false,"given":"Jingya","family":"Wang","sequence":"first","affiliation":[{"name":"Key Lab of Health Technology Assessment of National Health Commission and Key Lab of Public Health Safety of Ministry of Education School of Public Health Fudan University Shanghai 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