{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T15:52:17Z","timestamp":1790092337630,"version":"4.0.1"},"reference-count":46,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T00:00:00Z","timestamp":1640822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>We investigated the agreement and accuracy of preoperative magnetic resonance imaging (MRI) with postoperative pathological characteristics and stages of endometrial endometrioid carcinoma (EEC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We recruited 527 women with EEC who underwent staging surgery at a single medical institution. The preoperative MRI, stages, and clinical and pathological parameters, including myometrial invasion (MI), cervical invasion (CI), adnexal metastasis (AM), intra\u2010abdominal metastasis, and pelvic and\/or para\u2010aortic nodal metastasis, were recorded and analyzed. The agreement and accuracy between the preoperative MRI findings and these parameters and stages were assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The rate of the preoperative MRI\u2010based clinical stage matching the postoperative surgical stage was 85.2% in International Federation of Gynecology and Obstetrics stage IA, 51.9% in stage IB, 35.5% in stage II, 5.3% in stage IIIA, 33.3% in stage IIIB, 28.6% in stage IIIC1, 64.3% in stage IIIC2, and 93.8% in stage IVB. The consistency between radiologists and pathologists was 80.5% for deep MI, 91.5% for cervical invasion, 92.2% for adnexal metastasis, 98.9% for intra\u2010abdominal metastasis, and 87.5% and 92.2% for pelvic and para\u2010aortic nodal metastases, respectively. The negative predictive value of intra\u2010abdominal metastasis was the highest with 99.8%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Preoperative MRI could be an excellent tool for routine preoperative assessment to predict pathological parameters and stages of EEC, especially in excluding intra\u2010abdominal metastatic disease.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.4486","type":"journal-article","created":{"date-parts":[[2021,12,30]],"date-time":"2021-12-30T12:13:34Z","timestamp":1640866414000},"page":"993-1004","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Preoperative magnetic resonance imaging predicts clinicopathological parameters and stages of endometrial carcinomas"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9431-5916","authenticated-orcid":false,"given":"Chia\u2010Ying","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology College of Medicine National Taiwan University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1442-0850","authenticated-orcid":false,"given":"Yi\u2010Jou","family":"Tai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology College of Medicine National Taiwan University  Taipei Taiwan"},{"name":"Department of Obstetrics and Gynecology National Taiwan University Hospital  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9187-1562","authenticated-orcid":false,"given":"I\u2010Lun","family":"Shih","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging College of Medicine National Taiwan University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8958-5222","authenticated-orcid":false,"given":"Ying\u2010Cheng","family":"Chiang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology College of Medicine National Taiwan University  Taipei Taiwan"},{"name":"Graduate Institute of Clinical Medicine College of Medicine National Taiwan University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9742-4752","authenticated-orcid":false,"given":"Yu\u2010Li","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology College of Medicine National Taiwan University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6817-0693","authenticated-orcid":false,"given":"Heng\u2010Cheng","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology College of Medicine National Taiwan University  Taipei Taiwan"},{"name":"Department of Obstetrics and Gynecology National Taiwan University Hospital  Xin\u2010Chu City Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3282-6304","authenticated-orcid":false,"given":"Wen\u2010Fang","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology College of Medicine National Taiwan University  Taipei Taiwan"},{"name":"Department of Obstetrics and Gynecology National Taiwan University Hospital  Taipei Taiwan"},{"name":"Graduate Institute of Oncology College of Medicine National Taiwan University  Taipei Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,12,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2018.6956"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21387"},{"key":"e_1_2_10_5_1","unstructured":"http:\/\/seer.cancer.gov\/statfacts\/html\/corp.html\u2006(accessed September 2021)."},{"key":"e_1_2_10_6_1","unstructured":"Taiwan Cancer Registry Task Force.Cancer registry annual report. 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