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However, knowledge of parents' psychotropic medication use following child's cancer diagnosis is scarce.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We use longitudinal Finnish register data on 3266 mothers and 2687 fathers whose child (aged 0\u201319) was diagnosed with cancer during 2000\u20132016. We record mothers' and fathers' psychotropic medication use (at least one annual purchase of anxiolytics, hypnotics, sedatives, or antidepressants) 5\u00a0years before and after the child's diagnosis and assess within\u2010individual changes in medication use by time since diagnosis, cancer type, child's age, presence of siblings, and parent's living arrangements and education using linear probability models with the individual fixed\u2010effects estimator. The fixed\u2010effects models compare each parent's annual probability of psychotropic medication use after diagnosis to their annual probability of medication use during the 5\u2010year period before the diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Psychotropic medication use was more common among mothers than fathers already before the child's diagnosis, 11.2% versus 7.3%. Immediately after diagnosis, psychotropic medication use increased by 6.0 (95% CI 4.8\u20137.2) percentage points among mothers and by 3.2 (CI 2.1\u20134.2) percentage points among fathers. Among fathers, medication use returned to pre\u2010diagnosis level by the second year, except among those whose child was diagnosed with acute lymphoblastic leukemia or lymphoblastic lymphoma. Among mothers of children with a central nervous system cancer, medication use remained persistently elevated during the 5\u2010year follow\u2010up. For mothers with other under\u2010aged children or whose diagnosed child was younger than 10\u00a0years, the return to pre\u2010diagnosis level was also slow.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Having a child with cancer clearly increases parents' psychotropic medication use. The increase is smaller and more short\u2010lived among fathers, but among mothers its duration depends on both cancer type and family characteristics. Our results suggest that an increased care burden poses particular strain to the long\u2010term mental well\u2010being of mothers.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.4662","type":"journal-article","created":{"date-parts":[[2022,3,28]],"date-time":"2022-03-28T22:01:41Z","timestamp":1648504901000},"page":"3145-3155","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Changes in parents' psychotropic medication use following child's cancer diagnosis: A fixed\u2010effects register\u2010study in Finland"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8813-3980","authenticated-orcid":false,"given":"Niina S.","family":"Mets\u00e4\u2010Simola","sequence":"first","affiliation":[{"name":"Population Research Unit University of Helsinki  Helsinki 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