{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T17:46:26Z","timestamp":1748972786208,"version":"3.40.5"},"reference-count":43,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T00:00:00Z","timestamp":1648080000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004564","name":"Ministarstvo Prosvete, Nauke i Tehnolo\u0161kog Razvoja","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Some studies did find significant differences in the level of depression of women while undergoing diagnostic evaluation of an abnormal Papanicolaou screening smear, but findings were not consistent. This study aimed to assess prevalence and correlates of depression in women with abnormal cervical screening results before and after diagnostic procedures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study was carried out during 2017 in a cohort of women with positive Papanicolaou screening test before and after diagnostic procedures (colposcopy\/biopsy\/endocervical curettage) at the university Clinical Centre Kragujevac, Serbia. Women completed a questionnaire about demographics, lifestyle, and other factors of interest. Also, questionnaire \u201cHospital Anxiety and Depression Scale\u201d (HADS) was used immediately before and 2\u20134\u00a0weeks after the diagnostic procedures: a score of \u22658 on HADS\u2010D and HADS\u2010A subscales indicated depression and anxiety, respectively. Multivariate logistic regression was applied in the data analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study comprised 172 women, giving a response rate of 72.3%. The mean age of the participants was 47.8\u00a0\u00b1\u00a011.1\u00a0years (range 23\u201365). The frequency of depressive symptoms was significantly higher after diagnostic procedures (48.3%) than before diagnostic procedures (37.2%) (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.038). Before diagnostic procedures, older age (OR\u00a0=\u00a01.60; 95% CI\u00a0=\u00a01.09\u20132.34; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.017), and level of anxiety according to the HADS\u2010A subscale (OR\u00a0=\u00a01.61; 95% CI\u00a0=\u00a01.38\u20131.88; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001) were significant independent predictors of depression. After diagnostic procedures, significant independent predictors of depression were urban place of residence (OR\u00a0=\u00a00.12; 95% CI\u00a0=\u00a00.03\u20130.47; <jats:italic>p<\/jats:italic>\u00a0=\u00a00.002) and level of anxiety according to the HADS\u2010A subscale (OR\u00a0=\u00a01.85; 95% CI\u00a0=\u00a01.54\u20132.21; <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our study showed that older age, rural residence, and anxiety play a role in shaping the risk of depression among women undergoing additional diagnostic procedures after receiving an abnormal Papanicolaou screening result.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.4709","type":"journal-article","created":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T22:51:47Z","timestamp":1648162307000},"page":"3518-3528","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Depression before and after diagnostic procedures among women with abnormal finding of Papanicolaou screening test"],"prefix":"10.1002","volume":"11","author":[{"given":"Irena","family":"Ilic","sequence":"first","affiliation":[{"name":"Faculty of Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goran","family":"Babic","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Faculty of Medical Sciences University of Kragujevac  Kragujevac Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Dimitrijevic","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Faculty of Medical Sciences University of Kragujevac  Kragujevac Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra Sipetic","family":"Grujicic","sequence":"additional","affiliation":[{"name":"Institute of Epidemiology, Faculty of Medicine University of Belgrade  Belgrade Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3229-4990","authenticated-orcid":false,"given":"Milena D.","family":"Ilic","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Faculty of Medical Sciences University of Kragujevac  Kragujevac Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,3,24]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(19)30482-6"},{"volume-title":"Cancer incidence in five continents. 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