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In our previous study, we identified and described regions of geographic clustering of <jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content> cases in Texas by analyzing ~1990 patients using two distinct cancer registries. In the current work, we describe in detail demographic patterns for this malignancy in our study population and apply logistic regression models to analyze the incidence of <jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content> by sex, race, age, and clinical stage at the time of diagnosis. Furthermore, using Fisher's exact test, we analyze changes in incidence over time in the identified Houston communities with unusually high <jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content> incidence. While <jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content> primarily affects Caucasian individuals &gt;55\u00a0years old, we confirm that it presents at a younger age and with more advanced disease stages in African\u2010American and Hispanic individuals. Also, we demonstrate a significant increase in <jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content> incidence over time in the identified communities. Spring, Katy, and Houston Memorial areas had high baseline rates. Furthermore, a statistically significant disease surge was observed in these areas after ~2005. This report supplements our initial study documenting the existence of geographic clustering of <jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content> cases in Texas and in greater detail describes demographic trends for our patient population. The observed surge in <jats:styled-content style=\"fixed-case\">CTCL<\/jats:styled-content> incidence in the three identified communities further argues that this malignancy may be triggered by one or more external etiologic agents.<\/jats:p>","DOI":"10.1002\/cam4.472","type":"journal-article","created":{"date-parts":[[2015,7,2]],"date-time":"2015-07-02T05:30:07Z","timestamp":1435815007000},"page":"1440-1447","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Demographic patterns of cutaneous T\u2010cell lymphoma incidence in Texas based on two different cancer registries"],"prefix":"10.1002","volume":"4","author":[{"given":"Ivan V.","family":"Litvinov","sequence":"first","affiliation":[{"name":"Division of Dermatology McGill University Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael T.","family":"Tetzlaff","sequence":"additional","affiliation":[{"name":"Section\u00a0of Dermatopathology Department of Pathology The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elham","family":"Rahme","sequence":"additional","affiliation":[{"name":"Division of Clinical Epidemiology McGill University Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle A.","family":"Jennings","sequence":"additional","affiliation":[{"name":"Section\u00a0of Dermatopathology Department of Pathology The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David R.","family":"Risser","sequence":"additional","affiliation":[{"name":"Cancer Epidemiology and Surveillance Branch Texas Cancer Registry Department of State Health Services Austin Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela","family":"Gangar","sequence":"additional","affiliation":[{"name":"Department of Dermatology The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Netchiporouk","sequence":"additional","affiliation":[{"name":"Division of Dermatology McGill University Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Moreau","sequence":"additional","affiliation":[{"name":"Division of Dermatology McGill University Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor G.","family":"Prieto","sequence":"additional","affiliation":[{"name":"Section\u00a0of Dermatopathology Department of Pathology The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denis","family":"Sasseville","sequence":"additional","affiliation":[{"name":"Division of Dermatology McGill University Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madeleine","family":"Duvic","sequence":"additional","affiliation":[{"name":"Department of Dermatology The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,7]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3502"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.1996.tb00311.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.7.854"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2012.06.010"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04567.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428190802136368"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08852.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.09.063"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.4161\/15384101.2014.947759"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-14-0307"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-2879"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12039"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2012.717695"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.4161\/15384101.2014.965061"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-11-251926"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2005.09.013"},{"key":"e_1_2_7_18_1","first-page":"201","article-title":"Mycosis fungoides in husband and wife","volume":"82","author":"Wooldridge W. 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