{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T02:04:11Z","timestamp":1725501851934},"reference-count":16,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2015,6,24]],"date-time":"2015-06-24T00:00:00Z","timestamp":1435104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The diagnostic accuracy of fine needle aspiration cytology (<jats:styled-content style=\"fixed-case\">FNAC<\/jats:styled-content>) of head and neck lesions is relatively high, but cytologic interpretation might be confusing if the sample is lacking typical cytologic features according to labeled site by physician. These errors may have an impact on pathology search engines, healthcare costs or even adverse outcomes. The cytology archive database of multiple institutions in southern Iran and Australia covering the period 2001\u20132011, were searched using keywords: salivary gland, head, neck, <jats:styled-content style=\"fixed-case\">FNAC<\/jats:styled-content>, and cytology. All the extracted reports were reviewed. The reports which showed discordance between the clinician's impression of the organ involved and subsequent fine needle biopsy request, and the eventual cytological diagnosis were selected. The cytological diagnosis was confirmed by histology or cell block, with assistance from imaging, clinical outcome, physical examination, molecular studies, or microbiological culture. The total number of 10,200 head and neck superficial <jats:styled-content style=\"fixed-case\">FNAC<\/jats:styled-content> were included in the study, from which 48 cases showed discordance between the clinicians request and the actual site of pathology. Apart from the histopathology, the imaging, clinical history, physical examination, immunohistochemical study, microbiologic culture and molecular testing helped to finalize the target organ of pathology in 23, 6, 7, 8, 2, and 1 cases respectively. The commonest discrepancies were for <jats:styled-content style=\"fixed-case\">FNAC<\/jats:styled-content> of \u201csalivary gland\u201d [total: 20 with actual final pathology in: bone (7), soft tissue (5), lymph node (3), odontogenic (3) and skin (2)], \u201clymph node\u201d [total: 12 with final pathology in: soft tissue (3), skin (3), bone (1) and brain (1)], \u201csoft tissue\u201d [total: 11 with final pathology in: bone (5), skin (2), salivary gland (1), and ocular region (1)] and \u201cskin\u201d [total: 5 with final pathology in: lymph node (2), bone (1), soft tissue (1) and salivary gland (1)]. The primary physician requesting <jats:styled-content style=\"fixed-case\">FNAC<\/jats:styled-content> of head and neck lesions are incorrect in their clinical impression of the actual site in nearly 0.5 percent of cases, due to the overlapping clinical and imaging findings or possibly due to inadequate history taking or physical examination.<\/jats:p>","DOI":"10.1002\/cam4.489","type":"journal-article","created":{"date-parts":[[2015,6,25]],"date-time":"2015-06-25T05:08:47Z","timestamp":1435208927000},"page":"1374-1380","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Discrepancy of target sites between clinician and cytopathological reports in head neck fine needle aspiration: Did I miss the target or did the clinician mistake the organ site?"],"prefix":"10.1002","volume":"4","author":[{"given":"Mahsa","family":"Khanlari","sequence":"first","affiliation":[{"name":"Department of Cytopathology Dr. Daneshbod Pathology Laboratory  Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yahya","family":"Daneshbod","sequence":"additional","affiliation":[{"name":"Department of Cytopathology Dr. Daneshbod Pathology Laboratory  Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanieh","family":"Shaterzadeh Yazdi","sequence":"additional","affiliation":[{"name":"Department of Pathology School of Veterinary Medicine Shiraz University  Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadegh","family":"Shirian","sequence":"additional","affiliation":[{"name":"Department of Pathology Shahrekord University, School of Veterinary Medicine  Shahrekord Iran"},{"name":"Shefa Neuroscience Research Center Khatam\u2010Al\u2010Anbia Hospital  Tehran Iran"},{"name":"Brain and Spinal Cord Injury Research Center Tehran University of Medical Sciences  Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahrzad","family":"Negahban","sequence":"additional","affiliation":[{"name":"Department of Cytopathology Dr. Daneshbod Pathology Laboratory  Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azita","family":"Aledavood","sequence":"additional","affiliation":[{"name":"Department of Cytopathology Dr. Daneshbod Pathology Laboratory  Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad","family":"Oryan","sequence":"additional","affiliation":[{"name":"Department of Pathology School of Veterinary Medicine Shiraz University  Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bijan","family":"Khademi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Shiraz University of Medical Sciences  Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khosrow","family":"Daneshbod","sequence":"additional","affiliation":[{"name":"Department of Cytopathology Dr. Daneshbod Pathology Laboratory  Shiraz Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Field","sequence":"additional","affiliation":[{"name":"Hospital and University of Notre Dame Medical School Sydney  Fremantle Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,24]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Histology for pathologists","author":"Sternberg S. 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