{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:47:13Z","timestamp":1761864433912,"version":"3.40.5"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,6,19]],"date-time":"2022-06-19T00:00:00Z","timestamp":1655596800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Prevention and early intervention can improve survival and quality of life across all cancers. Patient understanding of risk factors and associated actionable lifestyle changes and screening programs is not well understood by clinicians<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An Internet\u2010based tool, <jats:italic>Reduce My Risk<\/jats:italic>, was created in 2009 and made available on <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/oncolink.org\">oncolink.org<\/jats:ext-link>. Users voluntarily completed a survey regarding demographics and cancer risk factors, and received information about their cancer risk<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty eight thousand and one surveys were completed from 2009 to 2019. Median age was 26\u2009years (18\u2013101); 60% were females, 87% lived in North America, and 37% had at least a bachelor's degree. Users reported on behavioral\/ modifiable risk factors: 13% were current smokers, 52% were current consumers of alcohol, and 8% of those had \u226514 drinks\/week. Body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>) was \u226530 in 19%; 74% of all surveys reported dietary risks and 36% reported infrequent exercise. Excess <jats:styled-content style=\"fixed-case\">UV<\/jats:styled-content> exposure was reported by 19%. Among women, 36% reported performing breast self\u2010examinations monthly, and 50% reported receiving clinician breast examinations at least once every 3\u2009years. Sixty seven percent of men 55\u201375\u2009years reported screening prostate specific antigen testing, with 50% receiving annual digital rectal examinations. Nonmodifiable risk factors included family cancer history (64%), genetic syndrome (3%), and cancer\u2010predisposing health conditions (26%)<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Ninety\u2010seven percent of users reported modifiable risk factors, and 60% reported \u22654 of these risk factors. Understanding detailed characteristics of a large number of respondents has the potential to improve educational interventions to reduce cancer risk through behavioral modification and cancer screening across the general public.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.4952","type":"journal-article","created":{"date-parts":[[2022,6,20]],"date-time":"2022-06-20T04:45:11Z","timestamp":1655700311000},"page":"1744-1761","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Design and implementation of an <scp>Internet\u2010Based<\/scp> cancer risk assessment tool: Use over 10\u2009years"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1662-5086","authenticated-orcid":false,"given":"Michael J.","family":"LaRiviere","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"O'Keefe","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maribel","family":"Carpenter","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hann\u2010Hsiang","family":"Chao","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of Pennsylvania  Philadelphia Pennsylvania USA"},{"name":"Department of Radiation Oncology, Hunter Holmes McGuire Veterans Administration Medical Center  Richmond Virginia USA"},{"name":"Department of Radiation Oncology, Virginia Commonwealth University  Richmond Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella","family":"Amaniera","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolyn","family":"Vachani","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret K.","family":"Hampshire","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christina","family":"Bach","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Arnold\u2010Korzeniowski","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James M.","family":"Metz","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Hill\u2010Kayser","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,6,19]]},"reference":[{"volume-title":"Fulfilling the potential of cancer prevention and early detection","year":"2003","author":"Curry S.J.","key":"e_1_2_8_2_1"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05467-z"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.2196\/jmir.1223"},{"key":"e_1_2_8_5_1","article-title":"Coverage error in internet surveys: who web\u2010only surveys miss and how that affects results","volume":"22","author":"Keeter S","year":"2015","journal-title":"Pew Research Center"},{"key":"e_1_2_8_6_1","first-page":"986","article-title":"Achievements in public health, 1900\u20131999: tobacco use\u2014United States, 1900\u20131999","volume":"48","author":"Prev., C.D.C","year":"1999","journal-title":"MMWR"},{"key":"e_1_2_8_7_1","unstructured":"Alcohol and Public Health. 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