{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:58:37Z","timestamp":1790733517050,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T00:00:00Z","timestamp":1663200000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004851","name":"New York City Department of Health and Mental Hygiene","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004851","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>While several studies have reported the association between 9\/11 exposure and cancer risk, cancer survival has not been well studied in the World Trade Center (WTC) exposed population. We examined associations of 9\/11\u2010related exposures with mortality in WTC Health Registry enrollees diagnosed with cancer before and after 9\/11\/2001.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>This is a longitudinal cohort study of 5061 enrollees with a first\u2010ever primary invasive cancer diagnosis between 1995 and 2015 and followed through 2016. Based on the timing of first cancer diagnosis, pre\u20109\/11 (<jats:italic>n<\/jats:italic>\u00a0=\u00a0634) and post\u20109\/11 (<jats:italic>n<\/jats:italic>\u00a0=\u00a04427) cancer groups were examined separately. 9\/11\u2010related exposures included witnessing traumatic events, injury on 9\/11, and 9\/11\u2010related post\u2010traumatic stress disorder (PTSD). Associations of exposures with all\u2010cause mortality were examined using Cox proportional hazards regression. In the post\u20109\/11 group, cancer\u2010specific mortality was evaluated by enrollee group (WTC rescue\/recovery workers vs. non\u2010workers) using Fine and Gray's proportional sub\u2010distribution hazard models, adjusting for baseline covariates, tumor characteristics, and treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the pre\u20109\/11 group, 9\/11\u2010related exposures were not associated with all\u2010cause mortality. In the post\u20109\/11 group, increased risk of all\u2010cause mortality was associated with PTSD (adjusted HR\u00a0=\u00a01.35; 95% CI\u00a0=\u00a01.11\u20131.65), but not with injury or witnessing traumatic events. Cancer\u2010specific mortality was not statistically significantly associated with 9\/11\u2010related exposures. In rescue\/recovery workers, increased non\u2010cancer mortality risk was associated with PTSD (aHR\u00a0=\u00a02.13, 95% CI\u00a0=\u00a01.13\u20134.00) and witnessing \u22653 traumatic events (aHR\u00a0=\u00a02.00, 95% CI\u00a0=\u00a01.13\u20133.55).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We did not observe associations between 9\/11\u2010related exposures and cancer\u2010specific mortality. Similar to findings in the non\u2010cancer WTC exposed population, PTSD was associated with increased risk of all\u2010cause mortality in cancer patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.4992","type":"journal-article","created":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T15:04:55Z","timestamp":1663254295000},"page":"1829-1840","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Mortality after the 9\/11 terrorist attacks among world trade center health registry enrollees with cancer"],"prefix":"10.1002","volume":"12","author":[{"given":"Rebecca D.","family":"Kehm","sequence":"first","affiliation":[{"name":"New York City Department of Health and Mental Hygiene World Trade Center Health Registry  Long Island City New York USA"},{"name":"Department of Epidemiology Mailman School of Public Health, Columbia University  New York City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7812-8878","authenticated-orcid":false,"given":"Jiehui","family":"Li","sequence":"additional","affiliation":[{"name":"New York City Department of Health and Mental Hygiene World Trade Center Health Registry  Long Island City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin","family":"Takemoto","sequence":"additional","affiliation":[{"name":"New York City Department of Health and Mental Hygiene World Trade Center Health Registry  Long Island City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janette","family":"Yung","sequence":"additional","affiliation":[{"name":"New York City Department of Health and Mental Hygiene World Trade Center Health Registry  Long Island City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baozhen","family":"Qiao","sequence":"additional","affiliation":[{"name":"New York State Department of Health Bureau of Cancer Epidemiology  Albany New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R.","family":"Farfel","sequence":"additional","affiliation":[{"name":"New York City Department of Health and Mental Hygiene World Trade Center Health Registry  Long Island City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James E.","family":"Cone","sequence":"additional","affiliation":[{"name":"New York City Department of Health and Mental Hygiene World Trade Center Health Registry  Long Island City New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,15]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.22638"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djab165"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17197290"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jncics\/pkz090"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.23278"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2018.01.004"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13032-015-0029-y"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/jech-2019-212311"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S47150"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jts.21972"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.22588"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12940-019-0449-7"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-017-1764-5"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61180-X"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2012.300690"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17124344"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/003335491012500411"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.11164"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1121"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11524-008-9317-4"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2806"},{"key":"e_1_2_14_23_1","unstructured":"National Cancer Institute.SEER site recode ICD\u2010O\u20103\/WHO 2008 definition.2008. 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