{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,22]],"date-time":"2026-03-22T08:19:13Z","timestamp":1774167553994,"version":"3.50.1"},"reference-count":47,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T00:00:00Z","timestamp":1658880000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100019870","name":"Cancer Foundation of China","doi-asserted-by":"publisher","award":["CFC2020KYXM001"],"award-info":[{"award-number":["CFC2020KYXM001"]}],"id":[{"id":"10.13039\/501100019870","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81971650"],"award-info":[{"award-number":["81971650"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin City","doi-asserted-by":"publisher","award":["18JCYBJC92100"],"award-info":[{"award-number":["18JCYBJC92100"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Lung cancer screening may provide a \u201cteachable moment\u201d for the smoking cessation and relapse prevention. However, the impact of lung cancer screening on smoking initiation in non\u2010smokers has not been reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A baseline smoking behavior survey was conducted in 2000 participants who were screened by low\u2010dose computed tomography (LDCT) from 2014 to 2018. All participants were re\u2010surveyed on their smoking behavior in 2019. Of these, 312 participants were excluded, leaving 1688 participants in the final analysis. The smoking initiation rate in baseline non\u2010smokers, the relapse rate in baseline former smokers, and the abstinence rate in baseline current smokers were calculated, respectively. The associations between screening results, demographic characteristics, and smoking behavior change were analyzed using multivariable logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>From 2014 to 2019, smoking prevalence significantly decreased from 52.6% to 49.1%. The prevalence of smoking initiation, relapse, and abstinence in baseline non\u2010smokers, former, and current smokers was 16.8%, 22.9%, and 23.7%, respectively. The risk of smoking initiation in baseline non\u2010smokers was significantly higher in those with negative screening result (adjusted OR\u00a0=\u00a02.97, 95% CI: 1.27\u20136.94). Compared to smokers who only received baseline screening, the chance of smoking abstinence in baseline current smokers was reduced by over 80% in those who attended 5 rounds of screening (adjusted OR\u00a0=\u00a00.15, 95% CI:0.08\u20130.27). No significant associations were found between smoking relapse and prior screening frequency, with at least one positive screening result. Age, gender, occupational exposure, income, and smoking pack years were also associated with smoking behavior changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The overall decreased smoking prevalence indicated an overwhelming effect of \u201cteachable moment\u201d on \u201clicense to smoke.\u201d A tailored smoking cessation strategy should be integrated into lung cancer screening.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.5073","type":"journal-article","created":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T13:52:42Z","timestamp":1658929962000},"page":"4667-4678","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["The impact of low\u2010dose <scp>CT<\/scp> on smoking behavior among non\u2010smokers, former\u2010smokers, and smokers: A population\u2010based screening cohort in rural China"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3266-3373","authenticated-orcid":false,"given":"Zheng","family":"Su","sequence":"first","affiliation":[{"name":"Department of Cancer Epidemiology, National Cancer Center\/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuebing","family":"Li","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute Tianjin Medical University General Hospital  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heng","family":"Wu","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute Tianjin Medical University General Hospital  Tianjin 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Sichuan Lung Cancer Center, West China Hospital, Chengdu Sichuan University  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology Tianjin Medical University General Hospital  Tianjin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9294-0005","authenticated-orcid":false,"given":"Fang\u2010Hui","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Cancer Epidemiology, National Cancer Center\/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6380-0871","authenticated-orcid":false,"given":"Youlin","family":"Qiao","sequence":"additional","affiliation":[{"name":"Department of Cancer Epidemiology, National Cancer Center\/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"},{"name":"Center of Global Health, School of Population Medicine and Public Health Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6521-5123","authenticated-orcid":false,"given":"Qinghua","family":"Zhou","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Lung Cancer Metastasis and Tumor Microenvironment, Tianjin Lung Cancer Institute Tianjin Medical University General Hospital  Tianjin China"},{"name":"Sichuan Lung Cancer Institute, Sichuan Lung Cancer Center, West China Hospital, Chengdu Sichuan University  China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7246-8858","authenticated-orcid":false,"given":"Ya\u2010Guang","family":"Fan","sequence":"additional","affiliation":[{"name":"Tianjin Key Laboratory of Lung Cancer 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