{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:02:44Z","timestamp":1791525764005,"version":"4.3.4"},"reference-count":30,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,8,26]],"date-time":"2015-08-26T00:00:00Z","timestamp":1440547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Chang Gung Medical Research Program, Taiwan","award":["CMRPG3A1221-3"],"award-info":[{"award-number":["CMRPG3A1221-3"]}]},{"name":"Chang Gung Medical Research Program, Taiwan","award":["CMRPG391501-4"],"award-info":[{"award-number":["CMRPG391501-4"]}]},{"name":"Chang Gung Medical Research Program, Taiwan","award":["CMRPG3B1221-3"],"award-info":[{"award-number":["CMRPG3B1221-3"]}]},{"name":"Chang Gung Medical Research Program, Taiwan","award":["CORPG3C0311-2"],"award-info":[{"award-number":["CORPG3C0311-2"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study aimed to construct a scoring system developed exclusively from the preoperative data that predicts 1\u2010year postoperative mortality in patients with solid cancers. A total of 20,632 patients who had a curative resection for solid\u2010organ cancers between 2007 and 2012 at Chang Gung Memorial Hospital Linkou Medical Center were included in the derivation cohort. Multivariate logistic regression analysis was performed to develop a risk model that predicts 1\u2010year postoperative mortality. Patients were then stratified into four risk groups (low\u2010, intermediate\u2010, high\u2010, and very high\u2010risk) according to the total score (0\u201343) form mortality risk analysis. An independent cohort of 16,656 patients who underwent curative cancer surgeries at three other hospitals during the same study period (validation cohort) was enrolled to verify the risk model. Age, gender, cancer site, history of previous cancer, tumor stage, Charlson comorbidity index, American Society of Anesthesiologist score, admission type, and Eastern Cooperative Oncology Group performance status were independently predictive of 1\u2010year postoperative mortality. The 1\u2010year postoperative mortality rates were 0.5%, 3.8%, 14.6%, and 33.8%, respectively, among the four risk groups in the derivation cohort (c\u2010statistic, 0.80), compared with 0.9%, 4.2%, 14.6%, and 32.6%, respectively, in the validation cohort (c\u2010statistic, 0.78). The risk stratification model also demonstrated good discrimination of long\u2010term survival outcome of the four\u2010tier risk groups (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.01 for both cohorts). The risk stratification model not only predicts 1\u2010year postoperative mortality but also differentiates long\u2010term survival outcome between the risk groups.<\/jats:p>","DOI":"10.1002\/cam4.518","type":"journal-article","created":{"date-parts":[[2015,8,27]],"date-time":"2015-08-27T01:08:57Z","timestamp":1440637737000},"page":"1687-1696","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["A simple risk stratification model that predicts 1\u2010year postoperative mortality rate in patients with solid\u2010organ cancer"],"prefix":"10.1002","volume":"4","author":[{"given":"Wen\u2010Chi","family":"Chou","sequence":"first","affiliation":[{"name":"Department of Medical Oncology Chang Gung Memorial Hospital at LinKou  Taoyuan Taiwan"},{"name":"Graduate Institute of Clinical Medical Sciences College of Medicine Chang Gung University  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Wang","sequence":"additional","affiliation":[{"name":"Departments of Surgery Chang Gung Memorial Hospital at LinKou  Taoyuan Taiwan"},{"name":"Department of Surgery School of Medicine University of Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu\u2010Fan","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Radiology Chang Gung Memorial Hospital at Kaoshiung  Kaoshiung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao\u2010Fen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Chang Gung Memorial Hospital at Chiayi  Chiayi Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang\u2010Hsien","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Chang Gung Memorial Hospital at Chiayi  Chiayi Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng\u2010Hsu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Chang Gung Memorial Hospital at Keelung  Keelung Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yung\u2010Chang","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Chang Gung Memorial Hospital at LinKou  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ta\u2010Sen","family":"Yeh","sequence":"additional","affiliation":[{"name":"Graduate Institute of Clinical Medical Sciences College of Medicine Chang Gung University  Taoyuan Taiwan"},{"name":"Departments of Surgery Chang Gung Memorial Hospital at LinKou  Taoyuan Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,8,26]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-011-1594-6"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-009-1051-z"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199506000-00011"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-013-3375-x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2003.11.012"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2007.06.307"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3181d5f95c"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.8813"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000482"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2663-1"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318216f56e"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-011-1671-x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-0947-x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.05.0658"},{"key":"e_1_2_7_16_1","unstructured":"Cancer Statistics.Taiwan Cancer Registry. 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