{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:29:11Z","timestamp":1790785751176,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,1,29]],"date-time":"2023-01-29T00:00:00Z","timestamp":1674950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","award":["FEDER: programme op\u00e9rationnel FEDER\u2010FSE Bourgogne"],"award-info":[{"award-number":["FEDER: programme op\u00e9rationnel FEDER\u2010FSE Bourgogne"]}],"id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006364","name":"Institut National Du Cancer","doi-asserted-by":"publisher","award":["Projet INCa\u2010SHS\u2010ESP, n\u00b02018\u2010124"],"award-info":[{"award-number":["Projet INCa\u2010SHS\u2010ESP, n\u00b02018\u2010124"]}],"id":[{"id":"10.13039\/501100006364","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The excess mortality observed in Acute Myeloblastic Leukaemia (AML) patients, partly attributed to unequal access to curative treatments, could be linked to care pathways.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included 1039 AML incident cases diagnosed between 2012\u20132016 from the 3 French blood cancer registries (3,625,400 inhabitants). We describe patients according to age, the medical entry unit and access to the specialised haematology unit (SHU) during follow\u2010up. Multivariate logistic regression model was done to determine the association between covariables and access to SHU. A total of 713 patients (69%) had access to SHU during care.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The most common care pathway concerned referral from the general practitioner to SHU, <jats:italic>n<\/jats:italic>\u00a0=\u00a0459(44%). The univariate analysis observed a downward trend for the most deprived patients. Patients who consulted in SHU were younger (66\u2009years vs. 83, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and 92% had access to cytogenetic analysis (vs. 54%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). They also had less poor prognosis AML\u2010subtypes (AML\u2010MRC, t\u2010AML\/MDS and AML\u2010NOS) (38% vs. 69%); 77% with de novo AML (vs. 67%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.003)], more favourable cytogenetic prognostic status (23% vs. 6%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), less comorbidities (no comorbidity\u00a0=\u00a055% vs. 34%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and treatments proposed were curative 68% (vs. 5.3%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Factors limiting access to SHU were age over 80\u2009years (OR, 0.14; 95% CI, 0.04\u20130.38), severe comorbidities (OR, 0.39; 95% CI, 0.21\u20130.69), emergency unit referral (OR, 0.28; 95% CI, 0.18\u20130.44) and non\u2010SHU referral (OR, 0.12; 95% CI, 0.07\u20130.18). Consultation in an academic hospital increased access to SHU by 8.87 times (95% CI, 5.64\u201314.2).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The high proportion of access to cytogenetic testing and curative treatment among patients admitted to SHU, and the importance of early treatment in AML underlines the importance of access to SHU for both diagnosis and treatment.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.5645","type":"journal-article","created":{"date-parts":[[2023,1,30]],"date-time":"2023-01-30T05:03:44Z","timestamp":1675055024000},"page":"8911-8923","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Factors influencing access to specialised haematology units during acute myeloblastic leukaemia patient care: A population\u2010based study in France"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8588-3831","authenticated-orcid":false,"given":"Kueshivi Midodji","family":"Atsou","sequence":"first","affiliation":[{"name":"Registre des H\u00e9mopathies Malignes de la C\u00f4te\u2010d'Or CHU de Dijon Bourgogne  Dijon France"},{"name":"UMR INSERM 1231 Universit\u00e9 Bourgogne Franche\u2010Comt\u00e9  Dijon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5837-7773","authenticated-orcid":false,"given":"Bernard","family":"Rachet","sequence":"additional","affiliation":[{"name":"Inequalities in Cancer Outcomes Network, Department of Non\u2010communicable Disease Epidemiology, Faculty of Epidemiology and Population Health London School of Hygiene &amp; 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