{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T13:29:38Z","timestamp":1789565378300,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T00:00:00Z","timestamp":1677456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>In high\u2010income countries, hope facilitates parental coping and builds the clinical relationship between families of children with cancer and their clinicians. However, the manifestation of hope in low\u2010 and middle\u2010income countries (LMICs) remains poorly understood. Our study explores Guatemalan parents' experiences with hope during the pediatric oncology diagnostic process and aims to identify discrete actions clinicians take to support hope.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This qualitative study utilized audio\u2010recordings of the diagnostic process and an additional semi\u2010structured interview for 20 families of children with cancer at Unidad Nacional de Oncolog\u00eda Pedi\u00e1trica in Guatemala. Spanish audio\u2010recordings were translated into English, transcribed, and coded using a priori and novel codes. Thematic content analysis using constant comparative methods explored parents' hopes and concerns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At diagnosis, Guatemalan parents expressed both hopes and concerns related to the entire cancer continuum. Throughout the diagnostic process, hope grew as concerns were alleviated. Clinicians supported hope by creating a supportive environment, providing information, affirming religious beliefs, and empowering parents. These strategies helped parents shift their focus from fear and uncertainty toward hope for their child's future. Parents expressed that establishing hope improved mood, promoted acceptance, and enabled them to care for themselves and their children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These results confirm the relevance of supporting hope in pediatric oncology settings in LMICs and suggest that culture informs hope\u2010related needs. Supporting hope is critical across cultures and can be integrated into clinical conversation using the four processes identified by our results.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.5725","type":"journal-article","created":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T10:08:50Z","timestamp":1677492530000},"page":"9966-9975","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Understanding hope at diagnosis: A study among Guatemalan parents of children with cancer"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5907-9989","authenticated-orcid":false,"given":"Anneliese H.","family":"Williams","sequence":"first","affiliation":[{"name":"Purdue University  West Lafayette Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Rivas","sequence":"additional","affiliation":[{"name":"Unidad Nacional de Oncolog\u00eda Pedi\u00e1trica  Guatemala City Guatemala"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Fuentes","sequence":"additional","affiliation":[{"name":"Unidad Nacional de Oncolog\u00eda Pedi\u00e1trica  Guatemala City Guatemala"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"C\u00e1ceres\u2010Serrano","sequence":"additional","affiliation":[{"name":"Unidad Nacional de Oncolog\u00eda Pedi\u00e1trica  Guatemala City Guatemala"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3435-8436","authenticated-orcid":false,"given":"Gia","family":"Ferrara","sequence":"additional","affiliation":[{"name":"St. Jude Children's Research Hospital  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tegan","family":"Reeves","sequence":"additional","affiliation":[{"name":"St. Jude Children's Research Hospital  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Antillon\u2010Klussmann","sequence":"additional","affiliation":[{"name":"Unidad Nacional de Oncolog\u00eda Pedi\u00e1trica  Guatemala City Guatemala"},{"name":"Francisco Marroquin University School of Medicine  Guatemala City Guatemala"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Rodriguez\u2010Galindo","sequence":"additional","affiliation":[{"name":"St. Jude Children's Research Hospital  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5791-4178","authenticated-orcid":false,"given":"Jennifer W.","family":"Mack","sequence":"additional","affiliation":[{"name":"Dana Farber Cancer Institute\/Boston Children's Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4541-6910","authenticated-orcid":false,"given":"Dylan E.","family":"Graetz","sequence":"additional","affiliation":[{"name":"St. Jude Children's Research Hospital  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2006.06.007"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-1193"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2014-2855"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/NCC.0b013e3182a453aa"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/NCC.0b013e318291ba7d"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30909-4"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.paid.2012.09.015"},{"key":"e_1_2_11_9_1","first-page":"157","volume-title":"Hope, Hopelessness, and Despair, in Atlas of the Heart","author":"Brown B","year":"2021"},{"issue":"3","key":"e_1_2_11_10_1","first-page":"22","article-title":"Faith development and collectivism among emerging adults in Guatemala and the United States","volume":"1","author":"Ashdown BK","year":"2012","journal-title":"Adv Psychol Study"},{"key":"e_1_2_11_11_1","volume-title":"The World Bank in Guatemala","year":"2020"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2020-004653"},{"key":"e_1_2_11_13_1","unstructured":"Guatemala. 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