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We aim to understand how the emergence of HPV has impacted race and SES survival disparities in OPSCC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective cohort of 18,362 OPSCC cases from 2010 to 2017 was assembled using the SEER (Surveillance, Epidemiology, and End Results) database. Cox proportional regression\u00a0and Fine and Gray regression models were used to calculate hazard ratios (HRs) adjusting for race, SES, age, subsite, stage, and treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Black patients had lower overall survival than patients of other races in HPV\u2010positive and HPV\u2010negative OPSCC (HR 1.31, 95% CI 1.13\u20131.53 and HR 1.23, 95% CI 1.09\u20131.39, respectively). Higher SES was associated with improved survival in all patients. Race had a diminished association with survival among high SES patients. Low SES Black patients had considerably worse survival than low SES patients of other races.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Race and SES interact variably across cohorts. High SES was protective of the negative effects of race, although there remains a disparity in outcomes among Black and non\u2010Black patients, even in high SES populations. The persistence of survival disparities suggests that the HPV epidemic has not improved outcomes equally across all demographic groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cam4.5726","type":"journal-article","created":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T05:28:50Z","timestamp":1677475730000},"page":"9976-9987","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Race and socioeconomic status interact with\n                    <scp>HPV<\/scp>\n                    to influence survival disparities in oropharyngeal squamous cell carcinoma"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9619-1256","authenticated-orcid":false,"given":"Emily Z.","family":"Yan","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Washington University School of Medicine  St. Louis Missouri 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