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However, there is a deficit of data on long\u2010term follow\u2010up and the recurrence status among these patients in the Chinese population. We analyzed real\u2010world follow\u2010up data of patients with CRLM who underwent hepatectomy, explored the recurrence patterns, and established a prediction model for a potential cure scenario.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent radical hepatic resection for CRLM during 2000\u20132016, with actual follow\u2010up data for at least 5 years, were enrolled. The observed survival rate was calculated and compared among the groups with different recurrence patterns. The predictive factors for 5\u2010year non\u2010recurrence were determined using logistic regression analysis; a recurrence\u2010free survival model was developed to predict long\u2010term survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 433 patients were included, of whom 113 patients were found non\u2010recurrence after 5 years follow\u2010up, with a potential cure rate of 26.1%. Patients with late recurrence (&gt;5 months) and lung relapse showed significantly superior survival. Repeated localized treatment significantly improved the long\u2010term survival of patients with intrahepatic or extrahepatic recurrences. Multivariate analysis showed that RAS wild\u2010type CRC, preoperative CEA &lt;10 ng\/ml, and liver metastases \u22643 were independent factors for a 5\u2010year disease\u2010free recurrence. A cure model was developed based on the above factors, achieving good performance in predicting long\u2010term survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>About one quarter patients with CRLM could achieve potential cure with non\u2010recurrence at 5\u2010year after surgery. The recurrence\u2010free cure model could well distinguish the long\u2010term survival, which would aid clinicians in determining the treatment strategy.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.5732","type":"journal-article","created":{"date-parts":[[2023,2,27]],"date-time":"2023-02-27T10:04:50Z","timestamp":1677492290000},"page":"9559-9569","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Five\u2010year survival post hepatectomy for colorectal liver metastases in a real\u2010world Chinese cohort: Recurrence patterns and prediction for potential cure"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7459-7319","authenticated-orcid":false,"given":"Yu\u2010Ming","family":"Su","sequence":"first","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education\/Beijing), Hepatopancreatobiliary Surgery Department I Peking University Cancer 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