{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:08:10Z","timestamp":1787162890007,"version":"build-2736575974"},"reference-count":22,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T00:00:00Z","timestamp":1680220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Encapsulated papillary carcinoma of the breast is rare, making difficult diagnosis and resulting in patients undergoing excision biopsy before definitive surgery. Evidence\u2010based guidelines are sparse. We would like to further elucidate the clinicopathological, treatment and survival outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>54 patients identified, with a median follow up duration of 48\u2009months. Patients' demographics, radiological and clinicopathological characteristics, treatment, adjuvant therapies as well as survival data were analysed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>18 (33.3%) cases were pure EPC, 12 (22.2%) were EPC associated with ductal carcinoma in situ (DCIS) and 24 (44.4%) cases had concurrent invasive ductal carcinoma. EPCs were more likely to present as a solid\u2010cystic mass on sonography (63.8%), regular\u2010shaped (oval or round) (97.9%), lack spiculations (95.7%) and lack suspicious microcalcifications (95.6%). Median tumour size was largest in the EPC with IDC group (18.5\u2009mm). 2 patients developed loco\u2010regional recurrence. Overall survival is good for EPCs of all subtypes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>EPC is a rare tumour with excellent prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cam4.5855","type":"journal-article","created":{"date-parts":[[2023,3,31]],"date-time":"2023-03-31T09:36:50Z","timestamp":1680255410000},"page":"11408-11416","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Encapsulated papillary carcinoma of the breast: An institutional case series and literature review"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5759-1700","authenticated-orcid":false,"given":"Hiang Jin","family":"Tan","sequence":"first","affiliation":[{"name":"SingHealth Duke\u2010NUS Breast Centre  Singapore Singapore"},{"name":"Department of Breast Surgery Singapore General Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puay Hoon","family":"Tan","sequence":"additional","affiliation":[{"name":"Division of Pathology Singapore General Hospital  Singapore Singapore"},{"name":"Duke\u2010NUS Medical School  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lester Chee Hao","family":"Leong","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology Singapore General Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronique Kiak Mien","family":"Tan","sequence":"additional","affiliation":[{"name":"SingHealth Duke\u2010NUS Breast Centre  Singapore Singapore"},{"name":"Department of Breast Surgery Singapore General Hospital  Singapore Singapore"},{"name":"Duke\u2010NUS Medical School  Singapore Singapore"},{"name":"Division of Surgery and Surgical Oncology National Cancer Centre Singapore  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benita Kiat Tee","family":"Tan","sequence":"additional","affiliation":[{"name":"SingHealth Duke\u2010NUS Breast Centre  Singapore Singapore"},{"name":"Department of Breast Surgery Singapore General Hospital  Singapore Singapore"},{"name":"Duke\u2010NUS Medical School  Singapore Singapore"},{"name":"Division of Surgery and Surgical Oncology National Cancer Centre Singapore  Singapore Singapore"},{"name":"Department of General Surgery (Breast service) Sengkang General Hospital  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue Zann","family":"Lim","sequence":"additional","affiliation":[{"name":"SingHealth Duke\u2010NUS Breast Centre  Singapore Singapore"},{"name":"Department of Breast Surgery Singapore General Hospital  Singapore Singapore"},{"name":"Duke\u2010NUS Medical School  Singapore Singapore"},{"name":"Division of Surgery and Surgical Oncology National 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Sean","family":"Yong","sequence":"additional","affiliation":[{"name":"SingHealth Duke\u2010NUS Breast Centre  Singapore Singapore"},{"name":"Department of Breast Surgery Singapore General Hospital  Singapore Singapore"},{"name":"Duke\u2010NUS Medical School  Singapore Singapore"},{"name":"Division of Surgery and Surgical Oncology National Cancer Centre Singapore  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yirong","family":"Sim","sequence":"additional","affiliation":[{"name":"SingHealth Duke\u2010NUS Breast Centre  Singapore Singapore"},{"name":"Department of Breast Surgery Singapore General Hospital  Singapore Singapore"},{"name":"Duke\u2010NUS Medical School  Singapore Singapore"},{"name":"Division of Surgery and Surgical Oncology National Cancer Centre Singapore  Singapore 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