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The main outcome is complete control (no vomiting episodes and\/or no more than mild nausea) of CINV. GRADE approach was used to rate the certainty of evidence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty\u2010eight RCTs with a total of 2503 patients were evaluated. Acupuncture in addition to UC may increase the complete control of acute vomiting (RR, 1.13; 95% CI, 1.02 to 1.25; 10 studies) and delayed vomiting (RR, 1.47; 95% CI, 1.07 to 2.00; 10 studies) when compared with UC only. No effects were found for all other review outcomes. The certainty of evidence was generally low or very low. None of the predefined moderators changed the overall findings, but in an exploratory moderator analysis we found that an adequate reporting of planned rescue antiemetics might decrease the effect size of complete control of acute vomiting (<jats:italic>p<\/jats:italic>\u2009=\u20090.035).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Acupuncture in addition to usual care may increase the complete control of chemotherapy\u2010induced acute vomiting and delayed vomiting but the certainty of evidence was very low. Well\u2010designed RCTs with larger sample sizes, standardized treatment regimens, and core outcome measures are needed.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.5962","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T04:46:01Z","timestamp":1684989961000},"page":"12504-12517","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Acupuncture for the prevention of chemotherapy\u2010induced nausea and vomiting in cancer patients: A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1904-5906","authenticated-orcid":false,"given":"Yuqian","family":"Yan","sequence":"first","affiliation":[{"name":"Institute for Complementary and Integrative Medicine University Hospital Zurich and University of Zurich  Zurich 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