{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T12:28:13Z","timestamp":1786969693445,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T00:00:00Z","timestamp":1692316800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,8,18]],"date-time":"2023-08-18T00:00:00Z","timestamp":1692316800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["CA016672"],"award-info":[{"award-number":["CA016672"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Survivors of SARS\u2010CoV\u20102 pneumonia often develop persistent respiratory symptom and interstitial lung abnormalities (ILAs) after infection. Risk factors for ILA development and duration of ILA persistence after SARS\u2010CoV\u20102 infection are not well described in immunocompromised hosts, such as cancer patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a prospective cohort study of 95 patients at a major cancer center and 45 patients at a tertiary referral center. We collected clinical and radiographic data during the index hospitalization for COVID\u201019 pneumonia and measured pneumonia severity using a semi\u2010quantitative radiographic score, the Radiologic Severity Index (RSI). Patients were evaluated in post\u2010COVID\u201019 clinics at 3 and 6\u2009months after discharge and underwent comprehensive pulmonary evaluations (symptom assessment, chest computed tomography, pulmonary function tests, 6\u2010min walk test). The association of clinical and radiological factors with ILAs at 3 and 6\u2009months post\u2010discharge was measured using univariable and multivariable logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sixty\u2010six (70%) patients of cancer cohort had ILAs at 3\u2009months, of whom 39 had persistent respiratory symptoms. Twenty\u2010four (26%) patients had persistent ILA at 6\u2009months after hospital discharge. In adjusted models, higher peak RSI at admission was associated with ILAs at 3 (OR 1.5 per 5\u2010point increase, 95% CI 1.1\u20131.9) and 6\u2009months (OR 1.3 per 5\u2010point increase, 95% CI 1.1\u20131.6) post\u2010discharge. Fibrotic ILAs (reticulation, traction bronchiectasis, and architectural distortion) were more common at 6\u2009months post\u2010discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Post\u2010COVID\u201019 ILAs are common in cancer patients 3\u2009months after hospital discharge, and peak RSI and older age are strong predictors of persistent ILAs.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cam4.6396","type":"journal-article","created":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T14:00:27Z","timestamp":1692626427000},"page":"17753-17765","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Interstitial lung abnormalities after hospitalization for COVID\u201019 in patients with cancer: A prospective cohort study"],"prefix":"10.1002","volume":"12","author":[{"given":"Sungryong","family":"Noh","sequence":"first","affiliation":[{"name":"Division of Critical Care, Pulmonary and Sleep Medicine McGovern Medical School  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Bertini","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine McGovern Medical School at UT Health  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"Mira\u2010Avendano","sequence":"additional","affiliation":[{"name":"Division of Critical Care, Pulmonary and Sleep Medicine McGovern Medical School  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Kaous","sequence":"additional","affiliation":[{"name":"Division of Critical Care, Pulmonary and Sleep Medicine McGovern Medical School  Houston Texas 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University of Texas MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara","family":"Bashoura","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine The University of Texas MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Adachi","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine The University of Texas MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott E.","family":"Evans","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine The University of Texas MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burton","family":"Dickey","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine The University of Texas MD Anderson 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