{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T13:23:27Z","timestamp":1789133007181,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"22","license":[{"start":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T00:00:00Z","timestamp":1698624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cancer is the second leading cause of death worldwide. Alongside other interventions, access to certain medicines may decrease cancer\u2010associated mortality. Listing medicines on national essential medicines lists may improve health outcomes. We examine the association between cancer mortality amenable to care and the listing of cancer medicines on national essential medicines lists (NEMLs) of 124 countries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this cross\u2010sectional study, we determined the number of medicines used to treat eight cancers on NEMLs and used multiple linear regression to analyze the association between cancer health outcome scores and the number of medicines on NEMLs while controlling for GDP. A sensitivity analysis was also conducted using selected medicines.<\/jats:p><\/jats:sec><jats:sec><jats:title>Findings<\/jats:title><jats:p>The number of cancer medicines on NEMLs was not associated with cancer health outcome scores when GDP was controlled for non\u2010melanoma skin (<jats:italic>p<\/jats:italic>\u2009=\u20090.224), uterine (<jats:italic>p<\/jats:italic>\u2009=\u20090.221), breast (<jats:italic>p<\/jats:italic>\u2009=\u20090.145), Hodgkin's lymphoma (<jats:italic>p<\/jats:italic>\u2009=\u20090.697), colon (<jats:italic>p<\/jats:italic>\u2009=\u20090.299), leukemia (<jats:italic>p<\/jats:italic>\u2009=\u20090.103), cervical (<jats:italic>p<\/jats:italic>\u2009=\u20090.834), and testicular cancers (<jats:italic>p<\/jats:italic>\u2009=\u20090.178).<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>There was a weak association between listing medicines for eight cancers in NEMLs and amenable mortality. Further studies are required to explore association between cancer health outcomes and other factors such as actual availability of medicines listed, access to surgeries, accurate diagnosis, radiotherapy, and early detection.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.6642","type":"journal-article","created":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T12:21:07Z","timestamp":1698668467000},"page":"20745-20758","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Essential cancer medicines and cancer outcomes: Cross\u2010sectional study of 124 countries"],"prefix":"10.1002","volume":"12","author":[{"given":"Oghenefejiro (Theresa)","family":"Ikpeni","sequence":"first","affiliation":[{"name":"MAP Centre for Urban Health Solutions St. Michael's Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5479-8327","authenticated-orcid":false,"given":"Darshanand","family":"Maraj","sequence":"additional","affiliation":[{"name":"MAP Centre for Urban Health Solutions St. Michael's Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Woods","sequence":"additional","affiliation":[{"name":"MAP Centre for Urban Health Solutions St. Michael's Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aine","family":"Workentin","sequence":"additional","affiliation":[{"name":"MAP Centre for Urban Health Solutions St. Michael's Hospital  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"Booth","sequence":"additional","affiliation":[{"name":"Department of Oncology Queen's University  Kingston Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3327-5580","authenticated-orcid":false,"given":"Nav","family":"Persaud","sequence":"additional","affiliation":[{"name":"MAP Centre for Urban Health Solutions St. Michael's Hospital  Toronto Ontario Canada"},{"name":"Department of Family and Community Medicine University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,30]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"StewartBW WildCP.World Cancer Report 2014. 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