{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T15:24:36Z","timestamp":1789226676902,"version":"build-2803163510"},"reference-count":52,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T00:00:00Z","timestamp":1704153600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Cancers of the head and neck (HN) are heterogeneous tumors with incidence rates varying globally. In Northern Europe oral and oropharyngeal cancers are the most common individual types. Survival for HN varies by individual tumor type but for most of them survival trends are not well known over extended periods of time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data for a retrospective survival study were obtained for Danish, Finnish, Norwegian, and Swedish patients from the NORDCAN database from 1971 to 2020. Relative 1\u2010 and 5\u2010year survival rates and 5\/1\u2010year conditional survival for years 2\u20135 were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Both 1\u2010 and 5\u2010year survival improved for all HN cancers but only marginally for laryngeal cancer. For the other cancers a 50\u2010year increase in 5\u2010year survival was about 30% units for nasopharyngeal and oropharyngeal cancers, 20% units for oral cancer and somewhat less for hypopharyngeal cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>5\u2010year survival reached about 65% for all HN cancers, except for hypopharyngeal cancer (30%). Human papilloma virus infection is becoming a dominant risk factor for the rapidly increasing oropharyngeal cancer, the prevention of which needs to emphasize oral sex as a route of infection.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.6867","type":"journal-article","created":{"date-parts":[[2024,1,2]],"date-time":"2024-01-02T08:24:54Z","timestamp":1704183894000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Survival in oral and pharyngeal cancers is catching up with laryngeal cancer in the NORDIC countries through a half\u00a0century"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7600-7143","authenticated-orcid":false,"given":"Frantisek","family":"Zitricky","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Biomedical Center in Pilsen Charles University in Prague  Pilsen Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anni I.","family":"Koskinen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2010 Head and Neck Surgery Helsinki University Hospital and University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otto","family":"Hemminki","sequence":"additional","affiliation":[{"name":"Department of Urology Helsinki University Hospital and University of Helsinki  Helsinki Finland"},{"name":"Cancer Gene Therapy Group, Translational Immunology Research Program University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asta","family":"F\u00f6rsti","sequence":"additional","affiliation":[{"name":"Hopp Children's Cancer Center (KiTZ)  Heidelberg Germany"},{"name":"Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) German Cancer Consortium (DKTK)  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7103-8530","authenticated-orcid":false,"given":"Akseli","family":"Hemminki","sequence":"additional","affiliation":[{"name":"Cancer Gene Therapy Group, Translational Immunology Research Program University of Helsinki  Helsinki Finland"},{"name":"Comprehensive Cancer Center Helsinki University Hospital  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2769-3316","authenticated-orcid":false,"given":"Kari","family":"Hemminki","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Biomedical Center in Pilsen Charles University in Prague  Pilsen Czech Republic"},{"name":"Division of Cancer Epidemiology, German Cancer Research Centre (DKFZ)  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,1,2]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41415-022-5166-x"},{"key":"e_1_2_12_3_1","first-page":"575","volume-title":"Personal Habits and Indoor Combustions","author":"IARC","year":"2012"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-020-00224-3"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-016582"},{"key":"e_1_2_12_6_1","first-page":"1","article-title":"IARC. 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