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This study assessed: (1) whether racial and ethnic minority patients and patients from neighborhoods with high social vulnerability index (SVI) experience a longer time to surgery after clinical diagnosis, and (2) whether time to surgery, race and ethnicity, and SVI are associated with upstaging to pT3\/pT4, disease\u2010free survival (DFS), and overall survival (OS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Arizona Cancer Registry (2009\u20132018) kidney and renal pelvis cases (<jats:italic>n<\/jats:italic>\u2009=\u20094592) were analyzed using logistic regression models to assess longer time to surgery and upstaging. Cox\u2010regression hazard models were used to test DFS and OS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Hispanic and AI patients with T1 tumors had a longer time to surgery than non\u2010Hispanic White patients (median time of 56, 55, and 45\u2009days, respectively). Living in neighborhoods with high (\u226575) overall SVI increased odds of a longer time to surgery for cT1a (OR 1.54, 95% CI: 1.02\u20132.31) and cT2 (OR 2.32, 95% CI: 1.13\u20134.73). Race and ethnicity were not associated with time to surgery. Among cT1a patients, a longer time to surgery increased odds of upstaging to pT3\/pT4 (OR 1.95, 95% CI: 0.99\u20133.84). A longer time to surgery was associated with PFS (HR 1.52, 95% CI: 1.17\u20131.99) and OS (HR 1.63, 95% CI: 1.26\u20132.11). Among patients with cT2 tumor, living in high SVI neighborhoods was associated with worse OS (HR 1.66, 95% CI: 1.07\u20132.57).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>High social vulnerability was associated with increased time to surgery and poor survival after surgery.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.7007","type":"journal-article","created":{"date-parts":[[2024,2,24]],"date-time":"2024-02-24T09:30:17Z","timestamp":1708767017000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Neighborhood social vulnerability and disparities in time to kidney cancer surgical treatment and survival in Arizona"],"prefix":"10.1002","volume":"13","author":[{"given":"Celina I.","family":"Valencia","sequence":"first","affiliation":[{"name":"Department of Family and Community Medicine, College of Medicine \u2013 Tucson The University of Arizona  Tucson Arizona 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