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Resected specimens were fixed in a perfluoropolyether\u2010filled test tube and scanned with a 3.0T and 9.4T MRI system ex\u00a0vivo. The residual tumor depth and MRI\u2010based tumor regression grade (TRG) were subjectively assessed and then compared with the pathological findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The ex\u00a0vivo 9.4T T2WI without fat suppression clearly differentiated tumor tissue, fibrosis and normal rectal wall, which clearly corresponded to the pathologic tissues of the rectal specimens. The TRG could be accurately assessed on ex\u00a0vivo 9.4T images in 13\/15 specimens (86.7%), while in 11\/15 specimens (73.3%) on ex\u00a0vivo 3.0T images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Ex vivo 9.4T MR imaging clearly displayed the components of rectal wall and proved excellent diagnostic performance for evaluating the treatment response to nCRT, which allow radiologists to understand and then assess more accurately the TRG of LARC after nCRT.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.70075","type":"journal-article","created":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T13:58:23Z","timestamp":1722520703000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Rectal adenocarcinoma: Ex\u00a0vivo 9.<scp>4T MRI<\/scp>\u2014correlation with histopathologic treatment response to neoadjuvant chemoradiotherapy"],"prefix":"10.1002","volume":"13","author":[{"given":"Zhihui","family":"Li","sequence":"first","affiliation":[{"name":"Department of Radiology, Ruijin Hospital Luwan Branch Shanghai Jiaotong University School of Medicine  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Changhai Hospital The Navy Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minglu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Changhai Hospital The Navy Medical University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"Bo","sequence":"additional","affiliation":[{"name":"Department of Radiology, Ruijin Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"},{"name":"Department of Endocrine and Metabolic 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