{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T07:15:20Z","timestamp":1793862920047,"version":"4.6.1"},"reference-count":37,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T00:00:00Z","timestamp":1711584000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Transoral robotic surgery (TORS) opens new perspectives. We evaluated the outcomes for patients having undergone TORS after previous radiotherapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective multicenter study (<jats:italic>n<\/jats:italic>\u2009=\u2009138) in a previously irradiated area between 2009 and 2020. Survival was assessed with the Kaplan\u2013Meier method. Prognostic factors were evaluated using a chi\u2010squared test, Fisher's test, or Wilcoxon's test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median length of hospital stay was 12.5\u2009days. Bleeding was the most frequent postoperative complication (15.2%, <jats:italic>n<\/jats:italic>\u2009=\u200922). Prophylactic vessel ligation did not significantly decrease bleeding. Complications were significantly lower for Tis, T1, and N0 tumors. 91.6% (<jats:italic>n<\/jats:italic>\u2009=\u2009120) of the patients with a perioperative tracheotomy could be decannulated. Larynx was functional for 65.94% of the patients. The median length of follow\u2010up was 26\u2009months. The 5\u2010year overall and relapse\u2010free survival rates were respectively 59.9% and 43.4%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Oncological and functional results confirmed the value of TORS as a treatment in previously irradiated area.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.7031","type":"journal-article","created":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T09:14:51Z","timestamp":1711617291000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Oncological and functional outcomes for transoral robotic surgery following previous radiation treatment for upper aerodigestive tract head and neck cancers. A French multicenter <scp>GETTEC<\/scp> group study"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1783-5066","authenticated-orcid":false,"given":"Olivier","family":"Malard","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Nantes University Hospital  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matilde","family":"Karakachoff","sequence":"additional","affiliation":[{"name":"Nantes Universit\u00e9, CHU Nantes, P\u00f4le Hospitalo\u2010Universitaire 11: Sant\u00e9 Publique, Clinique des donn\u00e9es, INSERM, CIC 1413  Nantes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Ferron","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery Nantes University Hospital  Nantes 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