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Patients in the obese group were then subdivided into four groups: Group 1 (BMI 30.0\u201334.9\u2009kg\/m<jats:sup>2<\/jats:sup>), Group 2 (BMI 35.0\u201339.9\u2009kg\/m<jats:sup>2<\/jats:sup>), Group 3 (BMI 40.0\u201344.9\u2009kg\/m<jats:sup>2<\/jats:sup>), and Group 4 (BMI\u2009\u2265\u200945.0\u2009kg\/m<jats:sup>2<\/jats:sup>) to evaluate the association between degree of obesity and clinical outcomes. We performed propensity score matching, compared outcome variables between the groups, and conducted adjusted multivariate logistic regression analyses of postoperative outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 6778 patients diagnosed with thyroid cancer who underwent thyroidectomy were screened, of whom 1299 (19.2%) patients were obese. Patients in the obese group had higher total hospital charges (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and an increased risk of overall postoperative complications (34.7% vs. 30.5%, <jats:italic>p<\/jats:italic>\u2009=\u20090.023). Specifically, patients in the obese group had increased odds of respiratory complication (adjusted odds ratio (aOR) 1.66, 95% confidence interval (CI) [1.26\u20132.19]), acute renal failure (aOR 1.87, 95% CI [1.13\u20133.09]), and wound complication (aOR 2.77, 95% CI [1.21\u20136.37]) than those in the non\u2010obese group. Moreover, trend tests showed that the risks of unfavorable discharge, infection, acute renal failure, and respiratory complication all exhibited an upward trend with increased BMI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Obesity is associated with an increased risk of postoperative complications in patients with thyroid cancer undergoing thyroidectomy. This finding suggests that obese patients should be treated with more caution during postoperative recovery.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.70335","type":"journal-article","created":{"date-parts":[[2024,10,17]],"date-time":"2024-10-17T10:25:54Z","timestamp":1729160754000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical Impact of Obesity on Postoperative Outcomes of Patients With Thyroid Cancer Undergoing Thyroidectomy: A 5\u2010Year Retrospective Analysis From the <scp>US<\/scp> National Inpatient Sample"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-0587-8072","authenticated-orcid":false,"given":"Yue","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Endocrinology and Diabetes Center The First Affiliated Hospital of Sun Yat\u2010sen University  Guangzhou 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