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Participants self\u2010reported any chronic physical or MHM. After having been presented with vignettes describing new onset symptoms (rectal bleeding or change in bowel habit), participants answered questions on symptom attribution and attitudes to investigations. Using multivariable logistic regression we examined the association between MHM and symptom attribution, intended help\u2010seeking, and willingness to undergo investigations, controlling for socio\u2010demographic factors and physical morbidities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Self\u2010reported MHM (reported by 14% of participants) was not associated with cancer symptom attribution (29% of participants with or without MHM mentioned cancer as a possible reason for rectal bleeding and 14% for change in bowel habit). Individuals with self\u2010reported MHM were less likely to contact a GP if experiencing a change in bowel habit (19% vs. 39%; adjusted (a)OR\u2009=\u20090.34, 95% CI 0.19\u20130.60) and to mention rectal bleeding to their GP (83% vs. 89%, aOR\u2009=\u20090.49, 95% CI 0.26\u20130.94). Although most participants would be willing to undergo a colonoscopy for these high\u2010risk symptoms, those with depression\/anxiety were less willing (90% vs. 96%; aOR: 0.37, 95% CI 0.16\u20130.87).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Individuals with self\u2010reported MHM are less likely to seek help and less willing to undergo investigations for high\u2010risk symptoms. Targeted support, for example, through additional mental health nurses, might facilitate prompt cancer diagnosis for the large group of people with MHM.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.70426","type":"journal-article","created":{"date-parts":[[2024,12,6]],"date-time":"2024-12-06T12:04:41Z","timestamp":1733486681000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Impact of Self\u2010Reported Long\u2010Term Mental Health Morbidity on Help\u2010Seeking and Diagnostic Testing for Bowel\u2010Related Cancer Symptoms: A Vignette Study"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-9185-9747","authenticated-orcid":false,"given":"Flavia","family":"Pennisi","sequence":"first","affiliation":[{"name":"PhD National Programme in One Health Approaches to Infectious Diseases and Life Science Research, Department of Public Health, Experimental and Forensic Medicine University of Pavia  Pavia Italy"},{"name":"School of Medicine Universit\u00e0 Vita\u2010Salute San Raffaele  Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni Emanuele","family":"Ricciardi","sequence":"additional","affiliation":[{"name":"PhD National Programme in One Health Approaches to Infectious Diseases and Life Science Research, Department of Public Health, Experimental and Forensic Medicine University of Pavia  Pavia Italy"},{"name":"School of Medicine Universit\u00e0 Vita\u2010Salute San Raffaele  Milano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"von Wagner","sequence":"additional","affiliation":[{"name":"Research Department of Behavioural Science and Health University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Smith","sequence":"additional","affiliation":[{"name":"Research Department of Behavioural Science and Health University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aradhna","family":"Kaushal","sequence":"additional","affiliation":[{"name":"Research Department of Behavioural Science and Health University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Lyratzopoulos","sequence":"additional","affiliation":[{"name":"Research Department of Behavioural Science and Health University College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel William David","family":"Merriel","sequence":"additional","affiliation":[{"name":"Centre for Primary Care &amp; 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