{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T03:16:27Z","timestamp":1776914187391,"version":"3.51.2"},"reference-count":59,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T00:00:00Z","timestamp":1737504000000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000982","name":"Conquer Cancer Foundation","doi-asserted-by":"publisher","award":["2021RG\u20106948019170"],"award-info":[{"award-number":["2021RG\u20106948019170"]}],"id":[{"id":"10.13039\/100000982","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Cancer patients in rural areas experience greater barriers to treatment access compared with patients in urban areas. There is limited research on how the COVID\u201019 pandemic affected cancer treatment delivery for rural patients who were also diagnosed with COVID\u201019. This study has two objectives: to assess (1) the urban\u2013rural differences in cancer care and (2) the predictors of cancer treatment delay or discontinuation (TDD) among patients diagnosed with COVID\u201019.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We used data from the American Society of Clinical Oncology Survey on COVID\u201019 in Oncology Registry (March 2020\u2013September 2022), which included cancer patients with test\u2010confirmed SARS\u2010CoV\u20102 infection (<jats:italic>N<\/jats:italic>\u2009=\u20093797). Data included patient sociodemographic characteristics, COVID\u201019 diagnosis information, cancer clinical characteristics, and changes to cancer treatment. Cancer TDD was defined as any scheduled treatment by more than 2\u2009weeks. Rurality was examined through both patient residence and oncology practice. We computed adjusted prevalence ratios (aPRs) using multivariable Poisson regressions to assess predictors of cancer TDD in urban and rural areas.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the study period, 44.1% of patients with COVID\u201019 experienced either cancer treatment delay or discontinuation and 5.7% experienced cancer treatment discontinuation. Controlling for other factors, receiving care in a rural oncology practice was associated with cancer TDD (aPR: 1.25, 95% CI: 1.01\u20131.55). Differences in cancer TDD were not found across rurality of patient residence. Among rural patients (<jats:italic>N<\/jats:italic>\u2009=\u2009582), Hispanic\/Latinx cancer patients had greater prevalence of cancer TDD (aPR: 1.55, 95% CI: 1.04\u20132.33) compared with non\u2010Hispanic White cancer patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings can be used to inform programs and policies to minimize the impact of future public health emergencies on cancer care delivery in rural areas. Additional research is needed to explore potential differences in cancer care delivery across urban and rural oncology practices and patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.70512","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T05:40:25Z","timestamp":1737610825000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Urban and Rural Differences in Cancer Treatment Disruption Among Patients With <scp>COVID<\/scp>\u201019: An Analysis of the US <scp>ASCO COVID<\/scp>\u201019 in Oncology Registry"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6808-6615","authenticated-orcid":false,"given":"Yu Chen","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Health Outcomes and Behavior Moffitt Cancer Center  Tampa Florida 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