{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T03:35:04Z","timestamp":1777088104390,"version":"3.51.4"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"vor","delay-in-days":12,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Breast cancer is the most commonly diagnosed cancer among women in Canada. Screening is effective in reducing breast cancer mortality through early cancer detection. However, data on individual social and medical characteristics contributing to variation in adherence to screening is limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using multivariable logistic regression, we analyzed self\u2010reported questions on engagement in screening mammography from five regions of the Canadian Partnership for Tomorrow's Health (CanPath), including the BC Generations Project (BCGP), Alberta's Tomorrow Project (ATP), the Ontario Health Study (OHS), Quebec's CARTaGENE, and the Atlantic Partnership for Tomorrow's Health Study (Atlantic PATH).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study population included 79,986 and 46,907 individuals aged 50\u201374 and 40\u201349\u2009years at study enrollment, respectively. Most participants self\u2010reported undergoing screening mammography less than 2\u2009years from study enrollment, ranging from 77.8% in OHS to 86.3% in BCGP. Factors significantly associated with a lower odd of ever undergoing screening mammography were lower household income, being single\/never married, current daily smoking, poor self\u2010perceived health, no history of breast feeding, and\u2009\u2265\u200924\u2009months since last routine medical check\u2010up by a doctor or nurse. Among women aged 40\u201349\u2009years with a first\u2010degree family history of breast cancer (<jats:italic>N<\/jats:italic>\u2009=\u20094212 [8.9%]), the likelihood of ever being screened varied by region and was significantly lower among individuals with post menopause and more than 12\u2009months since last medical check\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Factors associated with screening adherence that were identified in this study namely household income, self\u2010perceived health, and routine medical check\u2010ups should be considered as potential factors for targeting undeserved communities and increasing engagement in screening at both provincial and national levels. The observed variation in mammography among women aged 40 to 49\u2009years with family history of breast cancer, may inform the current guidelines for potential benefits of early screening initiation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.70543","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T05:44:07Z","timestamp":1741931047000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Provincial Variation in Adherence to Breast Cancer Screening in Canada: Evidence From the Canadian Partnership for Tomorrow's Health"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2238-0564","authenticated-orcid":false,"given":"M.","family":"Darvishian","sequence":"first","affiliation":[{"name":"School of Population and Public Health University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1601-1604","authenticated-orcid":false,"given":"A.","family":"Moustaqim\u2010Barrette","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, McGill University  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Awadalla","sequence":"additional","affiliation":[{"name":"Ontario Institute for Cancer Research  Toronto Ontario Canada"},{"name":"Department of Molecular Genetics University of Toronto  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Bhatti","sequence":"additional","affiliation":[{"name":"School of Population and Public Health University of British Columbia  Vancouver British Columbia Canada"},{"name":"Cancer Control Research, British Columbia (BC) Cancer  Vancouver British Columbia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Broet","sequence":"additional","affiliation":[{"name":"Department of Preventive and Social Medicine, \u00c9cole de Sant\u00e9 Publique Universit\u00e9 de Montr\u00e9al  Montreal Quebec Canada"},{"name":"Research Centre, CHU Sainte Justine  Montreal Quebec Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. A.","family":"Murphy","sequence":"additional","affiliation":[{"name":"School of Population and Public Health University of British Columbia  Vancouver British Columbia Canada"},{"name":"Cancer Control Research, British Columbia (BC) Cancer  Vancouver British Columbia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Skead","sequence":"additional","affiliation":[{"name":"Ontario Institute for Cancer Research  Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Urquhart","sequence":"additional","affiliation":[{"name":"Department of Community Health and Epidemiology Dalhousie University  Halifax Nova Scotia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Vena","sequence":"additional","affiliation":[{"name":"Alberta Health Services, Alberta's Tomorrow Project Cancer Research &amp; Analytics, Cancer Care Alberta  Edmonton Alberta Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. J. B.","family":"Dummer","sequence":"additional","affiliation":[{"name":"School of Population and Public Health University of British Columbia  Vancouver British Columbia Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.23.00348"},{"key":"e_1_2_10_3_1","unstructured":"Statistics Canada. Government of Canada \u201cTable\u00a013\u201010\u20100111\u201001 Number and Rates of New Cases of Primary Cancer by Cancer Type Age Group and Sex \u201d2022."},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-017-0339-7"},{"key":"e_1_2_10_5_1","article-title":"Effectiveness of Breast Cancer Screening: Systematic Review and Meta\u2010Analysis to Update the 2009 U.S. Preventive Services Task Force Recommendation","volume":"164","author":"Nelson H. 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