{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T16:53:42Z","timestamp":1794329622191,"version":"4.9.0"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T00:00:00Z","timestamp":1743552000000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study aimed to analyze the influence factors affecting catheter\u2010related bloodstream infection, catheter\u2010related thrombosis and catheter\u2010related local complication, respectively, and to explore the relationship among them, as well as the influence of catheter\u2010related bloodstream infection, catheter\u2010related thrombosis and catheter\u2010related local complication on cancer patients' death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The clinical data of 605 patients with solid tumors who underwent PICC from March 2019 to January 2020 in a Chinese hospital were retrospectively analyzed. Chi\u2010square test and logistic regression analyses were used to examine the influence factors affecting catheterrelated bloodstream infection, catheter\u2010related thrombosis and catheterrelated local complication, respectively, and their influence on cancer patients' death during the follow\u2010up period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The results of logistic regression analyses showed that gender, PICC vascular, PICC tip condition, whether anticoagulant therapy and thrombus location were influence factors of catheter\u2010related bloodstream infection (\n                      <jats:italic>p<\/jats:italic>\n                      &lt;\u20090.05), however, only whether anticoagulant therapy was risk factors of catheter\u2010related thrombosis [odds ratio (OR) =\u20097.549, 95% confidence interval (CI): 2.9\u201319.652,\n                      <jats:italic>p<\/jats:italic>\n                      &lt;\u20090.05]. In addition, surgical history, PICC tip condition and thrombus location were influence factors of catheter\u2010related local complication (\n                      <jats:italic>p<\/jats:italic>\n                      &lt;\u20090.05). Furthermore, the results showed that after adjusted by all variables, only catheter\u2010related bloodstream infection was risk factor of cancer patients' death (OR\u2009=\u200911.231, 95% CI: 3.23\u201339.053,\n                      <jats:italic>p<\/jats:italic>\n                      &lt;\u20090.05). However, catheter\u2010related thrombosis (OR\u2009=\u20090.793, 95% CI: 0.308\u20132.043,\n                      <jats:italic>p<\/jats:italic>\n                      &gt;\u20090.05) and catheter\u2010related local complication (OR\u2009=\u20091.815, 95% CI: 0.715\u20134.609,\n                      <jats:italic>p<\/jats:italic>\n                      &gt;\u20090.05) were not significantly associated with patients' death.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Overall, the influence factors of catheter\u2010related bloodstream infection, catheter\u2010related thrombosis and catheter\u2010related local complication were significantly different. Moreover, catheter\u2010related bloodstream infection was the risk factor of cancer patients' death. However, catheter\u2010related thrombosis and catheter\u2010related local complication were not significantly associated with patients' death.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cam4.70841","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T04:59:52Z","timestamp":1743742792000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Influence Factors Analyses of PICC\u2010Related Bloodstream Infection, PICC\u2010Related Venous Thrombosis, and Infected Puncture Site and Their Influence on Cancer Patients' Death: A Retrospective Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2194-3705","authenticated-orcid":false,"given":"Guizhen","family":"Weng","sequence":"first","affiliation":[{"name":"Department of Oncology Nursing Fujian Medical University Union Hospital  Fuzhou Fujian China"},{"name":"School of Nursing, Fujian Medical University  Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Oncology Nursing Fujian Medical University Union Hospital  Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suhui","family":"Zheng","sequence":"additional","affiliation":[{"name":"The Vascular Access Care Centre, Fujian Medical University Union Hospital  Fuzhou Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-019-05276-0"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2013.22.Sup5.S13"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2012.02.048"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacr.2013.06.003"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2020.1300"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-015-2740-7"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2024.05.003"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-13916-5"},{"key":"e_1_2_11_10_1","article-title":"Catheter Impregnation, Coating or Bonding for Reducing Central Venous Catheter\u2010Related Infections in Adults","volume":"3","author":"Lai N. 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