{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T08:08:54Z","timestamp":1778918934680,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["23EA1003"],"award-info":[{"award-number":["23EA1003"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["23FA1004"],"award-info":[{"award-number":["23FA1004"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["23JA1003"],"award-info":[{"award-number":["23JA1003"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003478","name":"Ministry of Health, Labour and Welfare","doi-asserted-by":"publisher","award":["23JA1004"],"award-info":[{"award-number":["23JA1004"]}],"id":[{"id":"10.13039\/501100003478","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JSPS KAKENHI JP22K17401"],"award-info":[{"award-number":["JSPS KAKENHI JP22K17401"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Limited data exist on occupational disparities in long\u2010term cancer mortality among the working\u2010age population in Japan. We examined occupational disparities in long\u2010term cancer survival, focusing on 10\u2010year survival outcomes among working\u2010age populations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective observational study used data from the Kanagawa Cancer Registry of 41,632 patients with cancer aged 20\u201365\u2009years who were diagnosed between 1992 and 2015, with a 10\u2010year follow\u2010up. Patients were classified into four occupational classes based on their longest\u2010held occupations (upper nonmanual, lower nonmanual, manual, and primary industry). The primary outcome was all\u2010cause mortality, and cancer\u2010specific mortality was the secondary outcome. Poisson regression was used to estimate the mortality rate ratios (MRRs) and 95% confidence intervals (CIs) for each occupational class, adjusted for sex, age, and year of diagnosis. Additional analyses were performed for common cancer sites (stomach, lung, colorectal, and breast).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>MRRs for all\u2010cause mortality were higher in lower nonmanual (MRR\u2009=\u20091.14, 95% CI 1.10\u20131.18), manual (MRR\u2009=\u20091.38, 95% CI 1.32\u20131.43), and primary industry workers (MRR\u2009=\u20091.19, 95% CI 1.09\u20131.31) than in upper nonmanual workers (professional and managerial occupations). Similar patterns were observed across common cancer sites and cancer\u2010specific mortality. Adjusting for cancer stage and treatment attenuated these disparities but did not eliminate them, particularly among manual workers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We observed occupational disparities in long\u2010term cancer mortality among working\u2010age populations in Japan, with manual workers experiencing worse survival outcomes. Promoting targeted interventions, healthy lifestyles, and early cancer detection for cancer survivors in the workplace are crucial for mitigating these disparities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cam4.71020","type":"journal-article","created":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T05:49:58Z","timestamp":1751521798000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Occupational Disparities in Cancer Survival Among the Working Population in Japan: 10\u2010Year Survival Analysis Using the Kanagawa Cancer Registry"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5132-4679","authenticated-orcid":false,"given":"Kazuhiko","family":"Watanabe","sequence":"first","affiliation":[{"name":"Center for Research of the Aging Workforce, University of Occupational and Environmental Health, Japan  Kitakyushu Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Kawachi","sequence":"additional","affiliation":[{"name":"Department of Social and Behavioral Sciences Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7616-355X","authenticated-orcid":false,"given":"Masayoshi","family":"Zaitsu","sequence":"additional","affiliation":[{"name":"Center for Research of the Aging Workforce, University of Occupational and Environmental Health, Japan  Kitakyushu Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,3]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"key":"e_1_2_12_3_1","unstructured":"Cancer Registry and Statistics \u201cCancer Information Service National Cancer Center Japan (Ministry of Health Labour and Welfare National Cancer Registry) \u201d accessed October 5 2024 https:\/\/ganjoho.jp\/reg_stat\/statistics\/stat\/summary.html."},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyae031"},{"key":"e_1_2_12_5_1","unstructured":"Ministry of Health Labour and Welfare \u201cAge of the 100\u2010Year Life \u2013 Current State of Employment Measures for the Elderly \u201d accessed November 11 2024 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