{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:04:09Z","timestamp":1792011849926,"version":"4.4.0"},"reference-count":227,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Multimodality therapy incorporating a combination of cytoreductive surgery (CRS), intraperitoneal (IP) and systemic therapy continues to evolve for peritoneal carcinomatosis (PC) However, treatment and outcomes vary depending on tumor of origin.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To develop Appropriate Use Criteria (AUC) guidelines to facilitate treatment decision\u2010making for patients with PC based on available evidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>The American Radium Society (ARS) multidisciplinary expert panel performed a comprehensive systematic review. Preferred Reporting Items for Systematic Reviews and Meta\u2010analyses (PRISMA) methodology was used. These studies were used to inform the expert panel, which then rated the appropriateness of various treatments in seven representative clinical scenarios through a well\u2010established modified Delphi consensus methodology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Treatment of PC is often treated with a combination of CRS and IP\u2009\u00b1\u2009systemic chemotherapy but specific recommendations exist for different tumor types and outcomes vary.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Treatment of PC is complex and varies depending on origin of primary tumor and extent of disease. These AUC assist in patient and treatment selection for different clinical scenarios.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A summary of recommendations is outlined to guide practitioners on the management of PC from different tumor origins.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cam4.71043","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T10:48:51Z","timestamp":1753181331000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Executive Summary of the American Radium Society Appropriate Use Criteria for the Management of Peritoneal Carcinomatosis From Different Tumor Origins: Systematic Review and Guidelines"],"prefix":"10.1002","volume":"14","author":[{"name":"Expert Panel Management of Peritoneal Carcinomatosis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Department of Surgery Rutgers Cancer Institute  New Brunswick New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sareena","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Gynecologic Oncology MetroHealth  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard","family":"Abood","sequence":"additional","affiliation":[{"name":"Department of Surgery Loyola University Stritch School of Medicine  Maywood Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Christenson","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, Department of Medicine Johns Hopkins University  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Anker","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology University of Vermont Larner College of Medicine  Burlington Vermont USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5357-1814","authenticated-orcid":false,"given":"Dmitriy","family":"Akselrod","sequence":"additional","affiliation":[{"name":"Department of Radiology University of Vermont Larner College of Medicine  Burlington Vermont USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3598-6709","authenticated-orcid":false,"given":"Christopher L.","family":"Hallemeier","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic College of Medicine  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishan R.","family":"Jethwa","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Mayo Clinic College of Medicine  Rochester Minnesota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ed","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of Washington  Seattle WA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Percy","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology City of Hope National Medical Center  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric D.","family":"Miller","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, James Cancer Center The Ohio State University  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil B.","family":"Newman","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of Texas San Antonio Health Science Center  San Antonio Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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