{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T15:41:01Z","timestamp":1785166861691,"version":"3.55.0"},"reference-count":64,"publisher":"Wiley","issue":"15","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2025,8]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Socioeconomic status' (SES) impact on distress during cancer survivorship has been insufficiently studied, although the consequences of low SES can be cumulative and adversely impact a person's ability to access resources required for improved health and quality of life.<\/jats:p>\n <\/jats:sec>\n \n Patients and Methods<\/jats:title>\n We conducted a prospective study involving newly diagnosed patients within 2\u2009months of diagnosis (t1), and at 6\u2010, 12\u2010, and 18\u2010month follow\u2010up (t2\u2013t4) using the Distress Thermometer (DT). Generalized Linear Mixed Models (GLMM) were used to test for changes in distress over time, with fixed effects of time, SES, and age.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Out of 1702 eligible patients, 965 completed the baseline DT (53% men, 60.5\u2009years); 779, 681, and 626 participated at follow\u2010ups. Out of 554 completers, 9% were chronically distressed, while 40.8% were never distressed. Distress decreased in 21.3%, increased in 11.0%, and 17.8% fluctuated over time. Low\u2010SES patients consistently had the highest rates of distress. Distress scores and the frequency of distress (DT \u2265\u20095) decreased over time in all SES and age groups: For DT mean scores, GLMM revealed a significant effect of time (\n \u03c7<\/jats:italic>\n 2<\/jats:sup>\n (3)\u2009=\u200972.0,\n p<\/jats:italic>\n \u2009<\u20090.001), but not of SES (\n \u03c7<\/jats:italic>\n 2<\/jats:sup>\n (2)\u2009=\u20095.9,\n p<\/jats:italic>\n \u2009=\u20090.052). For frequency of distress, there was a main effect of time (\n \u03c7<\/jats:italic>\n 2<\/jats:sup>\n (3)\u2009=\u200941.4,\n p<\/jats:italic>\n \u2009<\u20090.001) and SES (\n \u03c7<\/jats:italic>\n 2<\/jats:sup>\n (2)\u2009=\u200915.5,\n p<\/jats:italic>\n \u2009<\u20090.001). Younger patients (<\u200965\u2009years) consistently experienced more distress than older patients (\u2265\u200965\u2009years). For DT mean scores, GLMM showed an effect of time (\n \u03c7<\/jats:italic>\n 2<\/jats:sup>\n (3)\u2009=\u200972.1,\n p<\/jats:italic>\n \u2009<\u20090.001) and age (\n \u03c7<\/jats:italic>\n 2<\/jats:sup>\n (1)\u2009=\u200966.2,\n p<\/jats:italic>\n \u2009<\u20090.001). Similarly, for frequency of distress we found an effect of time (\n \u03c7<\/jats:italic>\n 2<\/jats:sup>\n (3)\u2009=\u200941.7,\n p<\/jats:italic>\n \u2009<\u20090.001) and\u00a0age (\n \u03c7<\/jats:italic>\n 2<\/jats:sup>\n (1)\u2009=\u200952.8,\n p<\/jats:italic>\n \u2009<\u20090.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Effective psychosocial interventions require a customized approach to decrease distress in vulnerable groups.<\/jats:p>\n <\/jats:sec>\n \n Trial Registration<\/jats:title>\n \n This study was registered in the International Clinical Trials Registry (NCT04620564,\n https:\/\/clinicaltrials.gov\/<\/jats:ext-link>\n )\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/cam4.71076","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T10:28:28Z","timestamp":1754044108000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Early Cancer Survivorship Distress Trajectories Associated With Socioeconomic Status and Age: Findings From a Multicenter Prospective Study"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6872-9805","authenticated-orcid":false,"given":"Anja","family":"Mehnert\u2010Theuerkauf","sequence":"first","affiliation":[{"name":"Department of Medical Psychology and Medical Sociology, Comprehensive Cancer Center Central Germany (CCCG) University Medical Center Leipzig Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8157-3836","authenticated-orcid":false,"given":"Ute","family":"Goerling","sequence":"additional","affiliation":[{"name":"Corporate Member of Freie Universit\u00e4t Berlin, Humboldt\u2010Universit\u00e4t zu Berlin, and Berlin Institute of Health, Charit\u00e9 Comprehensive Cancer Center Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Berlin 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zu Berlin, and Berlin Institute of Health, Charit\u00e9 Comprehensive Cancer Center Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4916-7500","authenticated-orcid":false,"given":"Beate","family":"Hornemann","sequence":"additional","affiliation":[{"name":"National Center for Tumor Diseases Dresden (NCT\/UCC) University Hospital Carl Gustav Carus Dresden Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6773-9406","authenticated-orcid":false,"given":"Ulrich","family":"Keilholz","sequence":"additional","affiliation":[{"name":"Corporate Member of Freie Universit\u00e4t Berlin, Humboldt\u2010Universit\u00e4t zu Berlin, and Berlin Institute of Health, Charit\u00e9 Comprehensive Cancer Center Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Berlin Germany"},{"name":"National Center for Tumor Diseases (NCT) Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8591-9339","authenticated-orcid":false,"given":"Florian","family":"Lordick","sequence":"additional","affiliation":[{"name":"Department of Medicine II (Oncology, Gastroenterology, Hepatology, and Pulmonology), Comprehensive Cancer Center Central Germany (CCCG) University of Leipzig Medical Center Leipzig Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6310-5879","authenticated-orcid":false,"given":"Olaf von dem","family":"Knesebeck","sequence":"additional","affiliation":[{"name":"Institute of Medical Sociology University Medical Center Hamburg\u2010Eppendorf Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5930-4573","authenticated-orcid":false,"given":"David","family":"Kissane","sequence":"additional","affiliation":[{"name":"School of Medicine University of 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