{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:20:25Z","timestamp":1787761225002,"version":"build-2784847793"},"reference-count":37,"publisher":"Wiley","issue":"21","license":[{"start":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:00:00Z","timestamp":1762473600000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100016290","name":"Insamlingsstiftelsen Cancer- och Allergifonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016290","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011727","name":"Stockholm l\u00e4ns landsting","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011727","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002794","name":"Cancerfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Treatment for metastatic colorectal cancer (mCRC) has seen great advances but may not be equally available for all patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate the impact of socioeconomic status on cancer\u2010specific survival after diagnosis of mCRC, with emphasis on potential temporal trends in the effect of income.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This population\u2010based cohort study, based on 90,620 patients diagnosed with colorectal cancer in Sweden during 2007\u20132021 and registered in CRCBaSe, identified 33,498 patients with mCRC through 2022. We used relative survival to estimate excess mortality rate ratios (EMRRs) with 95% confidence intervals (CIs) comparing net survival by income quartiles, adjusting for sex, age, calendar year, education, marital status and birth country.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>One\u2010year relative survival improved from 55% in 2007\u20132012 to 63% in 2017\u20132022. In the first years after the diagnosis of metastases there was an income gradient with the biggest contrast between high\u2010income and low\u2010income patients (EMRR (95% CI) at one year: 0.84 (0.81\u20130.88)). Year of mCRC diagnosis did not alter the effect of income on survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Despite significant improvements in cancer\u2010specific survival for mCRC over the last decades, socioeconomic disparities, particularly based on income, continue to affect survival outcomes. The impact of income remains consistent from 2007 to 2021.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cam4.71357","type":"journal-article","created":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T12:59:23Z","timestamp":1762520363000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Low Income Has a Negative Effect on Survival Following Diagnosis of Metastatic Colorectal Cancer\u2014A Population\u2010Based Cohort Study"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9297-1573","authenticated-orcid":false,"given":"Malin","family":"Ljunggren","sequence":"first","affiliation":[{"name":"Department of Molecular Medicine and Surgery Karolinska Institutet  Stockholm Sweden"},{"name":"Medical Unit of Trauma, Emergency Surgery and Orthopaedics Karolinska University Hospital  Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline 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