{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T08:01:11Z","timestamp":1789027271151,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"21","license":[{"start":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T00:00:00Z","timestamp":1762732800000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100007319","name":"Albert Einstein College of Medicine, Yeshiva University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30CA013330"],"award-info":[{"award-number":["P30CA013330"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UM1TR004400"],"award-info":[{"award-number":["UM1TR004400"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Artificial intelligence (AI) chatbots perform well in answering English cancer questions. For Spanish, their performance is unknown and may differ by free vs. paywall versions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We evaluated the quality (range: 1\u20135 points), actionability (range: 0\u2013100%), and readability (range: 1\u201313 grades) of six popular AI chatbots in responding to the 15 most searched Spanish questions regarding breast, prostate, and colon cancer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The quality of overall AI chatbot responses was good (mean [95% CI]: 3.5 [3.4\u20133.6] points), while the actionability was low (mean [95% CI]: 35.6% [30.8%\u201340.3%]). The readability was high\u2010school\u2010level (mean [95% CI]: 9.2 [8.8\u20139.6] grades), not concordant with the American Medical Association recommendation (\u2264\u20096th grade). The quality, actionability, and readability did not differ by free and paywall versions (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings suggested AI chatbots may generate good\u2010quality responses to Spanish cancer questions, regardless of free or paywall versions. However, further improvement in actionability and readability is needed to benefit Spanish\u2010speaking patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cam4.71364","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T16:31:17Z","timestamp":1762792277000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Artificial Intelligence Chatbots and Their Responses to Most Searched Spanish Cancer Questions"],"prefix":"10.1002","volume":"14","author":[{"given":"En","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Population Health Albert Einstein College of Medicine  Bronx New York USA"},{"name":"Cancer Epidemiology, Prevention, and Control Program Montefiore Einstein Comprehensive Cancer Center  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1898-180X","authenticated-orcid":false,"given":"Jesus D.","family":"Anampa","sequence":"additional","affiliation":[{"name":"Cancer Therapeutics Program Montefiore Einstein Comprehensive Cancer Center  Bronx New York USA"},{"name":"Department of Oncology Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Bernabe\u2010Ramirez","sequence":"additional","affiliation":[{"name":"Cancer Therapeutics Program Montefiore Einstein Comprehensive Cancer Center  Bronx New York USA"},{"name":"Department of Oncology Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Population Health Albert Einstein College of Medicine  Bronx New York USA"},{"name":"Cancer Epidemiology, Prevention, and Control Program Montefiore Einstein Comprehensive Cancer Center  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaonan","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Population Health Albert Einstein College of Medicine  Bronx New York USA"},{"name":"Cancer Epidemiology, Prevention, and Control Program Montefiore Einstein Comprehensive Cancer Center  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen R.","family":"Isasi","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Population Health Albert Einstein College of Medicine  Bronx New York USA"},{"name":"Department of Pediatrics Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alyson B.","family":"Moadel\u2010Robblee","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Population Health Albert Einstein College of Medicine  Bronx New York USA"},{"name":"Cancer Epidemiology, Prevention, and Control Program Montefiore Einstein Comprehensive Cancer Center  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Chu","sequence":"additional","affiliation":[{"name":"Cancer Therapeutics Program Montefiore Einstein Comprehensive Cancer Center  Bronx New York USA"},{"name":"Department of Oncology Albert Einstein College of Medicine  Bronx New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,11,10]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-020-00913-8"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/jncics\/pkad010"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2023.2947"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2023.2954"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.22275"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.27715"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jncics\/pkad015"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.18653\/v1\/2023.findings-emnlp.878"},{"key":"e_1_2_12_10_1","volume-title":"Lost in Translation: Large Language Models in Non\u2010English Content Analysis","author":"Nicholas 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