{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T11:26:54Z","timestamp":1786706814136,"version":"build-2736575974"},"reference-count":70,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000048","name":"American Cancer Society","doi-asserted-by":"publisher","award":["23YOUN25"],"award-info":[{"award-number":["23YOUN25"]}],"id":[{"id":"10.13039\/100000048","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008237","name":"Department of Surgery","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008237","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Climate\u2010related disruptions to the health system may impact cancer outcomes. This may be particularly true for prostate cancer, which greatly contributes to cancer burden while existing on a risk spectrum, leading some men to delay treatment even in advanced cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study included men diagnosed with metastatic prostate cancer from 2010 to 2020 within SEER\u2010supported counties that experienced a climate\u2010related natural disaster from 2012 to 2018. A smaller subgroup of \u201cmajor\u201d disasters was classified based on individual assistance from FEMA. Year of natural disaster was considered the index date, with 2\u2010year pre\u2010 and post\u2010disaster periods compared. Age\u2010standardized incidence\u2010based metastatic prostate cancer mortality (IBM) rates were extracted from SEER and adjusted for demographics. Counties were then compared 147 SEER counties without any climate\u2010related natural disaster.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 222 counties across 11 states experiencing a single disaster within the study period, covering an estimated 27,787,120 people. Compared to the index year, prostate cancer IBM was 15% higher (RR: 1.15, 95% CI 1.02\u20131.30) 1\u2010year post\u2010disaster and 28% higher (RR: 1.28, 95% CI 1.11\u20131.49) 2\u2009years post\u2010disaster. Associations were stronger among counties (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200950) experiencing a \u201cmajor\u201d disaster (RR: 1.21, 95% CI: 1.05\u20131.40) and 35% (RR: 1.35, 95% CI: 1.17\u20131.55) at 1 and 2\u2009years. In non\u2010exposed counties, this pattern was absent.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We report a significant, dose\u2010dependent change in mortality from metastatic prostate cancer following a climate\u2010related natural disaster. The reasons are speculative but may include delayed diagnosis, care fragmentation, and interruptions for treatments for advanced disease including chemotherapy and radio\u2010hormonal therapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cam4.71618","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T07:29:28Z","timestamp":1770881368000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluating Potential Impacts of Climate\u2010Related Natural Disasters on Subsequent Prostate Cancer Mortality"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0049-8529","authenticated-orcid":false,"given":"Alexander P.","family":"Cole","sequence":"first","affiliation":[{"name":"Department of Urology Brigham and Women's Hospital, Harvard Medical School  Boston Massachusetts USA"},{"name":"Center for Surgery and Public Health Brigham and Women's 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