{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T05:48:37Z","timestamp":1777009717738,"version":"3.51.4"},"reference-count":60,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction and Methods<\/jats:title>\n                    <jats:p>Cancer therapy\u2013related cardiac dysfunction (CTRCD) is a well established and potentially life\u2010threatening complication of contemporary oncologic treatment. Although comprehensive cardio\u2010oncology guidelines have been developed, their integration into routine hematology and oncology practice remains inconsistent. This consensus statement, developed by a multidisciplinary panel of cardio\u2010oncology experts, aims to provide practical, case\u2010based guidance to help oncology providers recognize, assess, and manage CTRCD across a spectrum of malignancies and cardiovascular presentations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Scenarios and Discussion<\/jats:title>\n                    <jats:p>We present representative clinical scenarios that illustrate real\u2010world challenges in cardio\u2010oncology and apply evidence\u2010based recommendations from current guidelines, including those from the European Society of Cardiology (ESC) and the International Cardio\u2010Oncology Society (ICOS)\u2014to support informed decision\u2010making. Key areas of focus include baseline cardiovascular risk stratification prior to initiating potentially cardiotoxic therapies, with an emphasis on biomarker and imaging surveillance strategies tailored to individual risk profiles. Also, this document outlines the application of guideline\u2010directed medical therapy (GDMT) for cancer patients with heart failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>By offering a structured, user\u2010friendly framework, this document seeks to bridge the implementation gap between oncology and cardiology disciplines. Our goal is to equip oncology providers with accessible tools that facilitate early recognition, consistent surveillance, and timely referral, thereby preserving cancer treatment intensity while minimizing cardiovascular morbidity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cam4.71682","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T10:25:48Z","timestamp":1774607148000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Standardizing the Clinical Approach to Cancer Therapy\u2010Related Cardiac Dysfunction: Applying Cardio\u2010Oncology Guidelines as a Practical Tool for Hematology and Oncology Providers"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0214-349X","authenticated-orcid":false,"given":"Abdelrahman","family":"Ali","sequence":"first","affiliation":[{"name":"Division of Cardiology University of Texas Medical Branch  Galveston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suparna C.","family":"Clasen","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Department of Medicine Indiana University School of Medicine  Indianapolis Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5433-4810","authenticated-orcid":false,"given":"Anne","family":"Blaes","sequence":"additional","affiliation":[{"name":"Division of Hematology, Oncology and Transplantation University of Minnesota  Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Casselli","sequence":"additional","affiliation":[{"name":"International Cardio\u2010Oncology Society  Tampa Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"Deswal","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Texas at MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan Halli","family":"Demeter","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases Mayo Clinic  Scottsdale Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregory","family":"Durm","sequence":"additional","affiliation":[{"name":"Indiana University Simon Comprehensive Cancer Center  Indianapolis Indiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anecita","family":"Fadol","sequence":"additional","affiliation":[{"name":"Department of Cardiology University of Texas at MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Ferrajoli","sequence":"additional","affiliation":[{"name":"Department of Leukemia, Division of Cancer Medicine University of Texas at MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael G.","family":"Fradley","sequence":"additional","affiliation":[{"name":"Division of Cardiology Hospital of the University of Pennsylvania  Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joerg","family":"Herrmann","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic  Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Borja","family":"Ibanez","sequence":"additional","affiliation":[{"name":"Centro Nacional de Investigaciones Cardiovasculares (CNIC) &amp; IIS Fundaci\u00f3n Jim\u00e9nez D\u00edaz, UAM &amp; CIBERCV  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sue","family":"Koob","sequence":"additional","affiliation":[{"name":"Preventive Cardiovascular Nurses Association  Madison Wisconsin USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bogda","family":"Koczwara","sequence":"additional","affiliation":[{"name":"Australian Research Centre for Cancer Survivorship, University of New South Wales, Sydney Australia, and Flinders Health and Medical Research Institute, Flinders University  Bedford Park Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kasey J.","family":"Leger","sequence":"additional","affiliation":[{"name":"Seattle Children's Hospital, University of Washington  Seattle Washington USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer E.","family":"Liu","sequence":"additional","affiliation":[{"name":"Cardiology Service, Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"L\u00f3pez\u2010Fern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Cardiology Department La Paz University Hospital, IdiPAZ Research Institute  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander R.","family":"Lyon","sequence":"additional","affiliation":[{"name":"Cardio\u2010Oncology Centre of Excellence Royal Brompton Hospital  London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. 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