{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T04:54:46Z","timestamp":1781585686982,"version":"3.54.5"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T00:00:00Z","timestamp":1777334400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2026,5]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objective<\/jats:title>\n We aimed to evaluate medical decisions regarding urinary tract infection (UTI), describe associated microorganisms, and assess potential risk factors for percutaneous nephrostomy\u2010related UTI (UTI\u2010PN).<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Oncological patients who underwent percutaneous nephrostomy (PN) were included. We assessed percutaneous nephrostomy procedure\u2010related UTI (UTI\u2010PNp) when the UTI occurred until 7\u2009days after the PN and percutaneous nephrostomy catheter\u2010related UTI (UTI\u2010PNc) when the UTI occurred >\u20097\u2009days after PN.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 734 PN procedures were performed (45.4% first catheter placement, 54.6% catheter replacement). Fever was the primary clinical indicator guiding treatment decisions for both UTI\u2010PNp (43.3%; 26\/60) and UTI\u2010PNc (44.6%; 99\/222). Leukocyturia, either alone or combined with turbid urine, foul\u2010smelling urine, or leukocytosis, influenced treatment decisions in 5.0% (3\/60) of UTI\u2010PNp cases and 17.1% (38\/222) of UTI\u2010PNc cases. No risk factors were identified for UTI\u2010PNp; however, the time between urinary tract obstruction and the placement of the PN for decompression increased the odds of developing UTI\u2010PNc. Among urine cultures, multidrug\u2010resistant bacteria accounted for 57.7% (41\/71) in cases with three to six antibiotic use episodes, compared to 42.3% (30\/269) of cases of multidrug\u2010sensitive bacteria (\n p<\/jats:italic>\n \u2009<\u20090.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Beyond the paramount importance of achieving an accurate infection diagnosis to mitigate the prevalence of multidrug\u2010resistant bacteria, our results highlight differences between UTI\u2010PNc and UTI\u2010PNp, including risk factors, underscoring the need for distinct approaches to UTI\u2010PN.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/cam4.71877","type":"journal-article","created":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:14:34Z","timestamp":1777436074000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Challenges in Diagnosing and Treating Percutaneous Nephrostomy\u2010Related Urinary Tract Infection in Cancer Patients: A Retrospective Cohort Study"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2074-1829","authenticated-orcid":false,"given":"Jeferson Rodrigo","family":"Zanon","sequence":"first","affiliation":[{"name":"Nephrology and Palliative Care Departments Jales Cancer Hospital (a Barretos Cancer Hospital Unit \u2013 Pius XII Foundation) Jales S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Jenn\u00e9","family":"Mimica","sequence":"additional","affiliation":[{"name":"Microbiology, Pathological Sciences, and Pediatrics Departments Santa Casa de Miseric\u00f3rdia de S\u00e3o Paulo Medical School S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Humberto Tavares Guerreiro","family":"Fregnani","sequence":"additional","affiliation":[{"name":"Barretos Cancer Hospital (Pius XII Foundation) Barretos S\u00e3o Paulo Brazil"},{"name":"A.C. Camargo Cancer Center S\u00e3o Paulo S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"dos Reis","sequence":"additional","affiliation":[{"name":"Barretos Cancer Hospital (Pius XII Foundation) Barretos S\u00e3o Paulo Brazil"},{"name":"Department of Gynecologic Oncology Barretos Cancer Hospital (Pius XII Foundation) Barretos S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21756"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2023.08.009"},{"key":"e_1_2_13_4_1","first-page":"22","article-title":"EAU Guidelines on Urological Infections","volume":"18","author":"Bonkat G.","year":"2017","journal-title":"European Association of Urology"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.0287"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199310283291808"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.08.094"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-018-1245-y"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2019.0289"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2023.08.021"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/sja.SJA_543_18"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000033002"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.179.3.2028003"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jradnu.2019.07.004"}],"container-title":["Cancer Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cam4.71877","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cam4.71877","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cam4.71877","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T04:20:40Z","timestamp":1781583640000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cam4.71877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,28]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1002\/cam4.71877"],"URL":"https:\/\/doi.org\/10.1002\/cam4.71877","archive":["Portico"],"relation":{},"ISSN":["2045-7634","2045-7634"],"issn-type":[{"value":"2045-7634","type":"print"},{"value":"2045-7634","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,28]]},"assertion":[{"value":"2025-07-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71877"}}