{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T13:19:13Z","timestamp":1787663953122,"version":"build-2736575974"},"reference-count":44,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T00:00:00Z","timestamp":1786060800000},"content-version":"vor","delay-in-days":6,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82270195"],"award-info":[{"award-number":["82270195"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["L244063"],"award-info":[{"award-number":["L244063"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["L244025"],"award-info":[{"award-number":["L244025"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018904","name":"Beijing Xisike Clinical Oncology Research Foundation","doi-asserted-by":"publisher","award":["Y\u2010Young 2023\u20100286"],"award-info":[{"award-number":["Y\u2010Young 2023\u20100286"]}],"id":[{"id":"10.13039\/100018904","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The influence of bone marrow (BM) involvement at diagnosis on hematopoietic stem cell (HSC) mobilization outcomes remains to be fully elucidated, particularly in the contemporary plerixafor era. To address this issue, this multicenter retrospective cohort study including four lymphoma treatment centers evaluated patients who underwent their first autologous HSC mobilization procedure between January 2017 and June 2023. Mobilization success was defined as achieving a minimum CD34+ cell yield \u2265\u20092.0\u2009\u00d7\u200910\n                    <jats:sup>6<\/jats:sup>\n                    cells\/kg. Propensity score matching (PSM) was performed to rigorously adjust for baseline confounders and ensure robust group comparisons. The study cohort comprised 669 patients, of whom 138 (20.6%) presented with BM involvement at the time of diagnosis. Analyzes revealed that mobilization success rates were highly comparable between patients with and without BM involvement, both before (79.0% versus [vs.] 81.2%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.563) and after (79.1% vs. 83.5%;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.500) PSM. Furthermore, the median CD34+ cell yield did not differ significantly between the 2 cohorts either before (3.2 vs. 3.7\u2009\u00d7\u200910\n                    <jats:sup>6<\/jats:sup>\n                    \/kg;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.192) or after (3.2 vs. 3.5\u2009\u00d7\u200910\n                    <jats:sup>6<\/jats:sup>\n                    \/kg;\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.639) PSM. These findings indicate that initial BM involvement does not significantly impair the success of HSC mobilization in patients with lymphoma, a conclusion that remained highly consistent even after controlling for baseline variables.\n                  <\/jats:p>","DOI":"10.1002\/cam4.72153","type":"journal-article","created":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T10:29:51Z","timestamp":1786098591000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Bone Marrow Involvement on the Success of Hematopoietic Stem Cell Mobilization in Patients With Lymphoma"],"prefix":"10.1002","volume":"15","author":[{"given":"Jie","family":"Lv","sequence":"first","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education\/Beijing), Department of Lymphoma Peking University Cancer Hospital &amp; Institute  Beijing 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Hospital  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0367-1411","authenticated-orcid":false,"given":"Weiping","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education\/Beijing), Department of Lymphoma Peking University Cancer Hospital &amp; Institute  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3479-2547","authenticated-orcid":false,"given":"Jun","family":"Zhu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education\/Beijing), Department of Lymphoma Peking University Cancer Hospital &amp; Institute  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Hematology Qingdao Central 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