{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:56:22Z","timestamp":1791262582112,"version":"4.1.0"},"reference-count":29,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T00:00:00Z","timestamp":1788912000000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004829","name":"Science and Technology Department of Sichuan Province","doi-asserted-by":"publisher","award":["2024JDKP0097"],"award-info":[{"award-number":["2024JDKP0097"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2026,9]]},"abstract":"ABSTRACT<\/jats:title>\n \n Objectives<\/jats:title>\n To determine the prevalence of self\u2010perceived burden (SPB), identify factors associated with SPB, and examine the associations of SPB with anxiety, depression, and quality of life (QOL) among patients with bladder cancer undergoing ileal conduit urinary diversion.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n This cross\u2010sectional study included 121 patients recruited from the Department of Urology at a tertiary hospital in China between January 2024 and June 2025. SPB was assessed as the primary outcome using the Self\u2010Perceived Burden Scale. Anxiety, depression, and QOL were assessed using the Hospital Anxiety and Depression Scale and the WHOQOL\u2010BREF, respectively. Correlation analyses were performed to examine the relationships between SPB and psychological symptoms and QOL, and multiple linear regression was used to identify factors independently associated with SPB.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Overall, 66.94% of participants experienced\n SPB<\/jats:styled-content>\n , including 36.36% with mild\n SPB<\/jats:styled-content>\n , 27.27% with moderate\n SPB<\/jats:styled-content>\n , and 3.31% with severe\n SPB<\/jats:styled-content>\n . The impaired physical mobility (\n t<\/jats:italic>\n \u2009=\u20093.266,\n p<\/jats:italic>\n \u2009=\u20090.003), self\u2010care ability (\n F<\/jats:italic>\n \u2009=\u20094.890,\n p<\/jats:italic>\n \u2009=\u20090.009), monthly household income (\n F<\/jats:italic>\n \u2009=\u20092.825,\n p<\/jats:italic>\n \u2009=\u20090.028), and caregiver health status (\n F<\/jats:italic>\n \u2009=\u20093.791,\n p<\/jats:italic>\n \u2009=\u20090.025) were significantly associated with\n SPB<\/jats:styled-content>\n .\n SPB<\/jats:styled-content>\n was positively correlated with anxiety (\n r<\/jats:italic>\n \u2009=\u20090.410,\n p<\/jats:italic>\n \u2009<\u20090.01) and depression (\n r<\/jats:italic>\n \u2009=\u20090.426,\n p<\/jats:italic>\n \u2009<\u20090.01) but negatively correlated with all\n QOL<\/jats:styled-content>\n domains (physiological, psychological, environmental and social relationships) (\n p<\/jats:italic>\n \u2009<\u20090.01). In the final multivariable model, anxiety, depression and monthly household income were independently associated with\n SPB<\/jats:styled-content>\n scores, collectively explaining 28.6% of the variance.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n SPB was common among patients with bladder cancer undergoing ileal conduit urinary diversion. Anxiety, depression, and lower monthly household income were independently associated with higher SPB, while SPB was negatively associated with QOL. These findings support the potential value of psychological assessment and targeted supportive care, although longitudinal and interventional studies are needed to determine causal relationships.<\/jats:p>\n <\/jats:sec>","DOI":"10.1002\/cam4.72253","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T06:25:50Z","timestamp":1789021550000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Factors Associated With Self\u2010Perceived Burden and Its Relationship With Quality of Life Among Patients With Bladder Cancer Undergoing Ileal Conduit Urinary Diversion: A Cross\u2010Sectional Study"],"prefix":"10.1002","volume":"15","author":[{"given":"Jia\u2010lu","family":"Xu","sequence":"first","affiliation":[{"name":"West China Hospital\/West China School of Nursing, Sichuan University Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chan\u2010qing","family":"Fan","sequence":"additional","affiliation":[{"name":"West China Hospital\/West China School of Nursing, Sichuan University Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying\u2010qiong","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Urology of West China Hospital Sichuan University Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0427-6976","authenticated-orcid":false,"given":"Xin\u2010ting","family":"Yang","sequence":"additional","affiliation":[{"name":"Wound Treatment Center of West China Hospital, Sichuan University Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuo","family":"Tan","sequence":"additional","affiliation":[{"name":"Colorectal Cancer Center of West China Hospital, Sichuan University\/West China School of Nursing, Sichuan University Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3885-7443","authenticated-orcid":false,"given":"Shi\u2010lin","family":"Gao","sequence":"additional","affiliation":[{"name":"Colorectal Cancer Center of West China Hospital, Sichuan University\/West China School of Nursing, Sichuan University Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9874-2253","authenticated-orcid":false,"given":"Ya\u2010li","family":"Tian","sequence":"additional","affiliation":[{"name":"West China Hospital\/West China School of Nursing, Sichuan University Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2315-1023","authenticated-orcid":false,"given":"Deng\u2010bin","family":"Liao","sequence":"additional","affiliation":[{"name":"Trauma Center of West China Hospital\/West China School of Nursing, Sichuan University Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9288-6333","authenticated-orcid":false,"given":"Hong\u2010fei","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology West China Hospital, Sichuan University\/West China School of Nursing, Sichuan University Chengdu Sichuan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8612-5880","authenticated-orcid":false,"given":"Chang\u2010qing","family":"Liu","sequence":"additional","affiliation":[{"name":"Trauma Center of West China Hospital\/West China School of Nursing, Sichuan University Chengdu Sichuan China"},{"name":"Medicine and Engineering Interdisciplinary Research Laboratory of Nursing & Materials, West China Hospital, Sichuan University Chengdu Sichuan 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