{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T04:48:45Z","timestamp":1791866925401,"version":"4.3.4"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:00:00Z","timestamp":1791763200000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The objective of this study was to verify that a strategy involving prophylactic exposure of the inferior parathyroid glands and preservation of their venous blood flow\u2014achieved through early identification and protection of their venous drainage\u2014can enhance the success rate of maintaining glandular perfusion and effectively reduce the incidence of postoperative hypoparathyroidism.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      This study included 600 patients who underwent total thyroidectomy with concomitant bilateral central neck dissection between November 2019 and December 2025. Patients were divided into two groups based on the surgical technique: Group A (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009244), in which a prophylactic approach was used to protect the venous drainage of the inferior parathyroid glands, and Group B (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009356), which underwent conventional in\u00a0situ preservation of the inferior parathyroid glands. A comparison was made between the two groups regarding both the percentage of inferior parathyroid glands successfully preserved in\u00a0situ and the incidence of postoperative hypoparathyroidism.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The rate of visualization of inferior parathyroid glands with optimal blood supply was significantly higher in Group A than in Group B (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Postoperation parathyroid hormone level in Group A was significantly higher than that in Group B (25.15 [19.39, 33.58]\u2009pg\/mL vs. 19.12 [9.82, 28.85] pg\/mL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). In Group A, the rates of postoperative hypoparathyroidism\u2014encompassing both transient and permanent forms\u2014were significantly lower than those in Group B (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The method of prophylactically exposing the inferior parathyroid glands and preserving their venous system\u2014termed prophylactic preservation of inferior parathyroid venous blood flow\u2014is achieved through early identification and protection of their venous drainage. This approach enhances the success rate of maintaining glandular blood supply and effectively reduces the incidence of postoperative hypoparathyroidism.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cam4.72360","type":"journal-article","created":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T04:30:09Z","timestamp":1791865809000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Effect of Prophylactic Protection of Inferior Parathyroid Gland Vein Blood Supply on Reducing Postoperative Hypoparathyroidism"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9731-1337","authenticated-orcid":false,"given":"Liping","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Breast and Thyroid Surgery Guiqian International Hospital  Guiyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dehao","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery Guiqian International Hospital  Guiyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0119-7658","authenticated-orcid":false,"given":"Shichao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery The First Affiliated Hospital of Army Medical University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery Guiqian International Hospital  Guiyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinhua","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery Guiqian International Hospital  Guiyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoxi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Breast and Thyroid Surgery Guiqian International Hospital  Guiyang China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,12]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/2715260"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.21037\/gs\u201020\u2010859"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jviscsurg.2013.04.003"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020\u2010021\u201002663\u20108"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020\u2010017\u20101377\u20103"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10843"},{"issue":"6","key":"e_1_2_13_8_1","first-page":"913","article-title":"The Continuing Development of the Technique of Thyroidectomy","volume":"73","author":"Thompson N. W.","year":"1973","journal-title":"Surgery"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.9676"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7493143"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423\u2010019\u201001751\u20108"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010197603000\u201000010"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2017.07.008"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2016.08.019"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0011"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2015.0020"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2014.11.001"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1530\/EDM\u201017\u20100015"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sult.2011.12.00"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2022.03.011"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10581"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1097\u20100347(199908)21:5<442::aid\u2010hed10>3.0.co;2\u2010z"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.21053\/ceo.2016.00724"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/8747680"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2019.02.013"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10030543"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.1530\/EC\u201017\u20100313"},{"key":"e_1_2_13_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00423\u2010016\u20101548\u20103"}],"container-title":["Cancer Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cam4.72360","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cam4.72360","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cam4.72360","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T04:30:14Z","timestamp":1791865814000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cam4.72360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":27,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/cam4.72360"],"URL":"https:\/\/doi.org\/10.1002\/cam4.72360","archive":["Portico"],"relation":{},"ISSN":["2045-7634","2045-7634"],"issn-type":[{"value":"2045-7634","type":"print"},{"value":"2045-7634","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"2026-07-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e72360"}}