{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:39:00Z","timestamp":1792809540197,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Electronic patient\u2010reported outcome (ePRO) systems support symptom monitoring after chemotherapy; however, their integration into structured nurse\u2010led oncology workflows remains limited. In this study, we aimed to develop and evaluate the short\u2010term feasibility and usability of a nurse\u2010led ePRO system for home\u2010based postchemotherapy symptom monitoring and structured nursing triage for cancer patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010arm feasibility study was conducted at a cancer center in Taiwan between April and September 2024 among adult patients requiring home\u2010based symptom monitoring after hospital\u2010based chemotherapy care. The nurse\u2010led digital system was designed to support weekly self\u2010reporting of 12 chemotherapy\u2010related symptoms using the Chemotherapy Toxicity Self\u2010Assessment Questionnaire. The system incorporated rule\u2010based triage categorization using green, orange, and red risk levels and predefined nurse response protocols. Feasibility outcomes included report adherence, triage alert management, and system performance. Usability was evaluated using the System Usability Scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Forty\u2010two patients submitted 306 symptom reports during the 8\u2010week monitoring period, corresponding to an overall adherence rate of 91.1%. Among all reports, 16.3% generated orange alerts requiring nurse follow\u2010up and 6.5% generated red alerts requiring urgent review. Fatigue, pain, and hand\u2013foot syndrome were the most frequently reported abnormal symptoms. All orange and red alerts had documented nursing review. The system met the predefined technical performance indicators during simulated load testing, and achieved a mean System Usability Scale score of 92.6\u2009\u00b1\u20096.46.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This nurse\u2010led ePRO system demonstrated favorable short\u2010term feasibility and usability for home\u2010based postchemotherapy symptom monitoring and structured nursing triage. These findings support the practicality of integrating structured ePRO monitoring into postchemotherapy nursing care. Further multicenter and comparative studies are warranted to evaluate long\u2010term engagement, scalability, and clinical outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cam4.72377","type":"journal-article","created":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T10:24:11Z","timestamp":1792664651000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development and Feasibility Evaluation of a Nurse\u2010Led\n                    <scp>ePRO<\/scp>\n                    System for Home\u2010Based Post\u2010Chemotherapy Symptom Management in Patients With Cancer"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6506-2761","authenticated-orcid":false,"given":"Chiao\u2010Chi","family":"Kuan","sequence":"first","affiliation":[{"name":"Graduate Institute of Medical Sciences, College of Medicine National Defense Medical University  Taipei City 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Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1122-0055","authenticated-orcid":false,"given":"Chiun","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Oncology National Taiwan University Hospital  Taipei City Taiwan"},{"name":"Department of Medical Oncology National Taiwan University Cancer Center  Taipei City Taiwan"},{"name":"Graduate Institute of Oncology, College of Medicine National Taiwan University  Taipei City Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8563-1378","authenticated-orcid":false,"given":"Chi\u2010Ming","family":"Chu","sequence":"additional","affiliation":[{"name":"College of Public Health National Defense Medical University  Taipei City Taiwan"},{"name":"Big Data Research Center, College of Medicine Fu\u2010Jen Catholic University  New Taipei City Taiwan"},{"name":"Department of Healthcare Administration and Medical 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