{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T23:00:46Z","timestamp":1769554846661,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T00:00:00Z","timestamp":1715817600000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Recent studies have found a high prevalence of hepatitis B virus (HBV) infection in patients with non\u2010Hodgkin's lymphoma (NHL), especially B\u2010cell non\u2010Hodgkin's lymphoma (B\u2010NHL). However, most studies did not classify it and analyze the correlation between HBV and its various subtypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The authors retrospectively analyzed 1424 patients with lymphoma. Differences in the prevalence of HBV infection in patients with different pathological types of lymphoma were analyzed. The clinical characteristics, progression\u2010free survival (PFS), and overall survival (OS) of HBV\u2010positive and negative B\u2010NHL subtypes were compared according to HBV infection.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The HBV infection rate in NHL patients was 7.65%, which was higher than that in HL patients (2.59%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The HBV infection rate in the B\u2010NHL was higher than that in the T\u2010cell non\u2010Hodgkin's lymphoma (T\u2010NHL) (8.14% vs. 4.95%). The HBV infection rate in the aggressive B\u2010NHL was similar to that of the indolent B\u2010NHL (8.30% vs. 7.88%), and the highest HBV infection rates were found in diffuse large B\u2010cell lymphoma and chronic lymphocytic leukemia\/small lymphocytic lymphoma, but no significant differences in clinical characteristics, PFS, and OS were seen between HBV\u2010positive and negative patients in the two subtypes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was an association between HBV infection and the development of NHL and HBV infection may play a role in the pathogenesis of B\u2010NHL, but not T\u2010NHL.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.7284","type":"journal-article","created":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T10:13:28Z","timestamp":1715854408000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Analysis of hepatitis B virus infection in 1424 patients with different pathological types of lymphoma (2018\u20132022): A real\u2010world, retrospective study"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6561-1302","authenticated-orcid":false,"given":"Zhaoxia","family":"Li","sequence":"first","affiliation":[{"name":"Department of Hematology The First Hospital of Jilin University  Changchun Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Hematology The First Hospital of Jilin University  Changchun Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yangzhi","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Hematology The First Hospital of Jilin University  Changchun Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haotian","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Hematology The First Hospital of Jilin University  Changchun Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Hematology The First Hospital of Jilin University  Changchun Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhe","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Hematology The First Hospital of Jilin University  Changchun Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bowen","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Hematology The First Hospital of Jilin University  Changchun Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luming","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Hematology The First Hospital of Jilin University  Changchun Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jihong","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Hematology The First Hospital of Jilin University  Changchun Jilin China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken H.","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Hematopathology Duke Cancer Institute, Duke University Medical Center  Durham North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4066-9473","authenticated-orcid":false,"given":"Ou","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Hematology The First Hospital of Jilin University  Changchun Jilin 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