{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T20:17:22Z","timestamp":1793823442189,"version":"4.6.1"},"reference-count":29,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100018556","name":"Science and Technology Program of Suzhou","doi-asserted-by":"publisher","award":["SYKJ202104"],"award-info":[{"award-number":["SYKJ202104"]}],"id":[{"id":"10.13039\/501100018556","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018556","name":"Science and Technology Program of Suzhou","doi-asserted-by":"publisher","award":["SYS2020112"],"award-info":[{"award-number":["SYS2020112"]}],"id":[{"id":"10.13039\/501100018556","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Medicine"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed to explore the association between patient\u2010reported items at different time points after hematopoietic stem cell transplantation (HSCT) and long\u2010term survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a study with 144 allogeneic HSCT patients, following them for 5\u2009years post\u2010transplantation. Data from the Functional Assessment of Cancer Therapy\u2010Bone Marrow Transplant (FACT\u2010BMT) questionnaire were collected before transplantation and at 1, 3, 6, 12, 18, 36, and 60\u2009months after transplantation. Demographic characteristics and survival status were also assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the 144 cases, the 5\u2010year overall survival (OS), progression\u2010free survival (PFS), non\u2010relapse mortality (NRM), and graft\u2010versus\u2010host disease\u2010free (GRFS) rates were 65%, 48%, 17%, and 36% respectively. Health\u2010related quality of life (HRQOL) showed a fluctuating pattern over 5\u2009years. Using a latent class mixed model, patients were classified into two groups based on their physical well\u2010being (PWB) scores during the 60\u2010month follow\u2010up. Class 1 had initially lower PWB scores, which gradually increased over time. In contrast, Class 2 maintained higher PWB scores with slight increases over time. Kaplan\u2013Meier survival analysis revealed that Class 1 had better OS (70.9% vs. 52.9%, <jats:italic>p<\/jats:italic>\u2009=\u20090.021), PFS (60.5% vs. 41.2%, <jats:italic>p<\/jats:italic>\u2009=\u20090.039), and GRFS (35.1% vs. 29.3%, <jats:italic>p<\/jats:italic>\u2009=\u20090.035) compared to Class 2.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patients who had higher initial PWB scores after HSCT demonstrated improved long\u2010term survival outcomes. The PWB score could serve as a valuable predictor for the prognosis of HSCT.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cam4.7409","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T15:34:43Z","timestamp":1720193683000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Patient\u2010reported physical well\u2010being predicts good long\u2010term survival of hematopoietic stem cell transplantation"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3327-9788","authenticated-orcid":false,"given":"Yin","family":"Lu","sequence":"first","affiliation":[{"name":"National Clinical Research Center for Hematologic Diseases  Suzhou China"},{"name":"Department of Hematology The First Affiliated Hospital of Soochow University  Suzhou China"},{"name":"Hematopoietic Transplant Institute, Soochow University  Suzhou China"},{"name":"Jiangsu Institute of Hematology, The 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