{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:50:17Z","timestamp":1760061017008,"version":"build-2065373602"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T00:00:00Z","timestamp":1557100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>A size increase of the gingiva can be a manifestation of\u00a0gingival\u00a0disease. While gingival lesions can affect periodontal tissue, only few reports described the association between peripheral giant\u2010cell granuloma (PGCG) with dental implants and their clinical management. Their clinical relevance is of a great interest since some lesions may lead to extensive bone resorption, esthetic alterations, or even tooth\/implant loss. To the author's best knowledge, no specific guidelines for the treatment of PGCG affecting dental implant in the esthetic zone have been reported. The aim of this paper was to report an extensive PGCG associated with a dental implant in the esthetic area and its surgical management.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>A 39\u2010year\u2010old suffered from concussive trauma on her anterior maxillary dentition leading to an expanded, purplish soft tissue lesion surrounding the implant provisional crown on right central maxillary incisor. After complete lesion excision, the implant neck was carefully and gently debrided. Histological analysis confirmed the diagnosis of PGCG. The patient was then evaluated weekly for the first 3 weeks then monthly. No episodes of recurrence were identified. After 16 weeks of undisturbed healing, a soft tissue augmentation via tunnel technique was elected as the first treatment option to improve esthetics. Final implant restoration was delivered. Follow up at 22 months from biopsy excluded any recurrence of PGCG with stability of peri\u2010implant soft tissues.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Excisional biopsy, careful removal of irritating factors, monitoring, and connective tissue grafting can esthetically improve a malpositioned implant and showed no recurrence over a period of 22 months.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cap.10056","type":"journal-article","created":{"date-parts":[[2019,3,22]],"date-time":"2019-03-22T01:43:33Z","timestamp":1553219013000},"page":"77-82","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Esthetic Management of Peripheral Giant Cell Granuloma Affecting a Dental Implant in the Esthetic Zone"],"prefix":"10.1002","volume":"9","author":[{"given":"Lorenzo","family":"Mordini","sequence":"first","affiliation":[{"name":"Department of Periodontology School of Dentistry Creighton University  Omaha NE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,6]]},"reference":[{"issue":"1","key":"e_1_2_11_2_1","first-page":"S183","article-title":"Manifestations of systemic diseases and conditions that affect the periodontal attachment apparatus: Case definitions and diagnostic considerations","volume":"89","author":"Albandar JM","journal-title":"Journal of Periodontology"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/839032"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e31829a8316"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874210601206010153"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090081"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2003.74.9.1381"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2006.08.003"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0714.2003.00126.x"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12706"},{"issue":"6","key":"e_1_2_11_11_1","first-page":"1153","article-title":"Peripheral giant cell granuloma associated with dental implants: a rare case report","volume":"24","author":"Ozden FO","year":"2009","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2009.11.007"},{"issue":"2","key":"e_1_2_11_13_1","first-page":"295","article-title":"Peripheral giant cell granuloma associated with a dental implant","volume":"19","author":"Bischof M","year":"2004","journal-title":"Int J Oral Maxillofac Implants"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1563\/AAID-JOI-D-13-00155"},{"issue":"10","key":"e_1_2_11_15_1","first-page":"529","article-title":"Peripheral giant cell granuloma associated with a dental implant. 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