{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:55:28Z","timestamp":1760061328455,"version":"build-2065373602"},"reference-count":17,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T00:00:00Z","timestamp":1565222400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Axenfeld\u2010Rieger syndrome (ARS), also known as Rieger syndrome, is a rare autosomal dominant condition defined by craniofacial, ocular, dental, periumbilical, and systemic anomalies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>This case report describes in detail a multidisciplinary approach to successfully restore the oral function and esthetics of a 22\u2010year\u2010old patient diagnosed with ARS. The patient's clinical evaluation revealed that the area corresponding with teeth #13, #12, #11, #21, #22, and #23 was occupied by four malformed and\/or deciduous teeth. The four anterior teeth were extracted, and socket preservation was performed using bovine\u2010derived porous bone mineral. Six months after extractions, two implants were placed in the location of the lateral incisors and additional bone graft was performed. Two months after the initial healing, a temporary fixed partial was delivered and 9 months after implant placement the implants were restored with a porcelain\u2010fused\u2010to\u2010metal fixed partial denture.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The use of implant\u2010supported fixed partial dentures to restore missing teeth in patients with ARS provides biological and mechanical advantages over conventional, fixed, or removable prosthodontics. Further evaluation is needed to determine the longevity and long\u2010term prognosis of dental implants in patients with ARS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cap.10065","type":"journal-article","created":{"date-parts":[[2019,4,6]],"date-time":"2019-04-06T06:03:06Z","timestamp":1554530586000},"page":"172-176","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Rieger Syndrome: Rehabilitation With Dental Implants"],"prefix":"10.1002","volume":"9","author":[{"given":"Flavia Q.","family":"Pirih","sequence":"first","affiliation":[{"name":"UCLA School of Dentistry  Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma\u00edsa","family":"Casarin","sequence":"additional","affiliation":[{"name":"School of Dentistry Federal University of Pelotas  RS Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeniffer","family":"Perussolo","sequence":"additional","affiliation":[{"name":"School of Dentistry State University of Maring\u00e1  Maring\u00e1 PR Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Ozaki","sequence":"additional","affiliation":[{"name":"UCLA School of Dentistry  Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o G.","family":"Carnio","sequence":"additional","affiliation":[{"name":"Private practice  Londrina Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo M.","family":"Camargo","sequence":"additional","affiliation":[{"name":"UCLA School of Dentistry  Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Galvan","sequence":"additional","affiliation":[{"name":"UCLA School of Dentistry  Los Angeles CA 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