{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:53:11Z","timestamp":1760061191601,"version":"build-2065373602"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T00:00:00Z","timestamp":1588982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Necrotizing periodontitis (NP) is an atypical and painful form of periodontal disease, it is described by a promptly progress of ulceration and destruction of periodontal tissues; the NP is commonly linked to HIV\u2010positive patients. The aim of this report is to present a rare case of severe necrotizing ulcerative periodontitis treated non\u2010surgically.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>A 28\u2010year\u2010old dark skin female patient was referred to a dentistry college with the main complaint of spontaneous gingival bleeding and enlargement, oral pain during deglutition and dental hypersensitivity. Clinical and radiographic examination revealed generalized severe periodontal destruction, extensive bleeding, increased biofilm presence and spontaneous suppuration. Medical exams were requested, red and white blood cells were evaluated and among those exams an enzyme\u2010linked immunosorbent assay for HIV\u20101 antibodies, the result reveled reagent to HIV\u20101. The diagnosis of NP was assigned based on periodontal parameters such as necrosis and ulceration of the coronal portion of interdental papillae and gingival margin. Treatment established was scaling and root planning plus antibiotics. At 3 months of treatment the clinical and periodontal condition were stable.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This case report highlights a severe and generalized form of NP, where periodontal non\u2010surgical associated with antimicrobials resulted in elimination of the gingival enlargement, necrosis and ulceration of the coronal portion of interdental papillae and significant improvement of periodontal parameters.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cap.10105","type":"journal-article","created":{"date-parts":[[2020,4,11]],"date-time":"2020-04-11T07:54:38Z","timestamp":1586591678000},"page":"59-63","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Severe Necrotizing Periodontitis in an HIV\u2010Infected Patient: Case Report and Non\u2010Surgical Treatment"],"prefix":"10.1002","volume":"11","author":[{"given":"Ricardo R. S.","family":"Fonseca","sequence":"first","affiliation":[{"name":"Laboratory of Virology Institute of Biological Sciences Federal University of Par\u00e1  Bel\u00e9m PA Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos A.","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Department of Periodontology University Center of State of Par\u00e1  Bel\u00e9m PA Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T\u00e2nia M. S.","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Department of Periodontology University Center of State of Par\u00e1  Bel\u00e9m PA Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosely M. S.","family":"Cavaleiro","sequence":"additional","affiliation":[{"name":"Department of Special Needs Care University Center of State of Par\u00e1  Bel\u00e9m PA Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvio A. F.","family":"Menezes","sequence":"additional","affiliation":[{"name":"Department of Periodontology University Center of State of Par\u00e1  Bel\u00e9m PA Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luiz F. A.","family":"Machado","sequence":"additional","affiliation":[{"name":"Laboratory of Virology Institute of Biological Sciences Federal University of Par\u00e1  Bel\u00e9m PA Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12941"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1998.tb02419.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.4103\/jisp.jisp_385_17"},{"issue":"4","key":"e_1_2_9_5_1","first-page":"98","article-title":"The severity, extent and recurrence of necrotizing periodontal disease in relation to HIV status and CD4+ T cell count","volume":"12","author":"Phiri R","year":"2010","journal-title":"J Int Acad Periodontol"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.20396\/bjos.v16i0.8651054"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.4317\/jced.50888"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2013.05.002"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9290.93470"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.12.1790"},{"issue":"1","key":"e_1_2_9_11_1","first-page":"71","article-title":"Necrotizing periodontal diseases in HIV\u2010infected Brazilian patients: a clinical and microbiologic descriptive study","volume":"43","author":"Ramos MP","year":"2012","journal-title":"Quintessence Int"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000324872"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sdj.2015.07.001"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2015.09.004"}],"container-title":["Clinical Advances in Periodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcap.10105","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cap.10105","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cap.10105","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cap.10105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T21:15:42Z","timestamp":1760044542000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1002\/cap.10105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,9]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1002\/cap.10105"],"URL":"https:\/\/doi.org\/10.1002\/cap.10105","archive":["Portico"],"relation":{},"ISSN":["2573-8046","2163-0097"],"issn-type":[{"type":"print","value":"2573-8046"},{"type":"electronic","value":"2163-0097"}],"subject":[],"published":{"date-parts":[[2020,5,9]]},"assertion":[{"value":"2019-09-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}