{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T21:06:07Z","timestamp":1781643967679,"version":"3.54.5"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,9,15]],"date-time":"2020-09-15T00:00:00Z","timestamp":1600128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Gingival enlargement (GE) due to anti\u2010epileptic drugs (AEDs) shows a high prevalence rate. However, lamotrigine, a newer AED, has not shown to induce GE. The present case report describes a rare case of GE in a patient with epilepsy under lamotrigine therapy for the past 3 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>In this report, successful management of lamotrigine\u2010influenced GE in a 24\u2010year\u2010old patient with epilepsy by gingivectomy followed by stringent oral hygiene protocol is presented.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The present case report suggests that, even this newer AED can cause GE and the oral hygiene status of the patients could be an important triggering factor.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cap.10123","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T12:56:45Z","timestamp":1598533005000},"page":"130-133","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Lamotrigine\u2010Induced Gingival Enlargement: An Older Problem Due to a Newer Drug \u2012 A Rare Case Report"],"prefix":"10.1002","volume":"12","author":[{"given":"Poornima","family":"Rajendran","sequence":"first","affiliation":[{"name":"Department of Periodontology Sri Ramakrishna Dental College and Hospital  Coimbatore Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,15]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.2007.03064.x"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2004.0055"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.1999.tb00175.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-37580-1.00018-4"},{"key":"e_1_2_10_6_1","first-page":"861","volume-title":"Antiepileptic Drugs","author":"Leach MJ","year":"1995"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0883073897012001041"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-199818040-00004"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.4.1018"},{"key":"e_1_2_10_10_1","first-page":"37","article-title":"Phenytoin, carbamazepine, sodium valproate induced cutaneus reactions","volume":"43","author":"Ghaffarpour M","year":"2005","journal-title":"Acta Medica Iranica"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00865474"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1964.0034"},{"key":"e_1_2_10_13_1","first-page":"834","volume-title":"Carranza's Clinical Periodontology","author":"Newman MG","year":"2011"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12264"},{"key":"e_1_2_10_15_1","first-page":"46","article-title":"Sodium dilantin gingival hyperplasia and conservative treatment: a case report","volume":"5","author":"Baden E","year":"1950","journal-title":"J Dent Med"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.11-S.2061"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1972.tb00635.x"}],"container-title":["Clinical Advances in Periodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cap.10123","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cap.10123","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cap.10123","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T00:49:20Z","timestamp":1760057360000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1002\/cap.10123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,15]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1002\/cap.10123"],"URL":"https:\/\/doi.org\/10.1002\/cap.10123","archive":["Portico"],"relation":{},"ISSN":["2573-8046","2163-0097"],"issn-type":[{"value":"2573-8046","type":"print"},{"value":"2163-0097","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,15]]},"assertion":[{"value":"2020-05-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-09-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}