{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T05:32:24Z","timestamp":1783229544889,"version":"3.54.6"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,8,29]],"date-time":"2021-08-29T00:00:00Z","timestamp":1630195200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"published-print":{"date-parts":[[2022,3]]},"abstract":"Introduction<\/jats:title>Although alveolar ridge preservation may minimize alveolar ridge shrinkage following tooth extraction, there is a paucity of data on the effects of alveolar ridge preservation on implant\u2010related outcomes. The purpose of this manuscript is to report on peri\u2010implantitis of an implant placed at a site that had alveolar ridge preservation three decades earlier, and the subsequent dislodgement of an approximately 1\u2010cm3<\/jats:sup> grafted bone specimen during degranulation 4 months after implant reversal.<\/jats:p><\/jats:sec>Case Presentation<\/jats:title>A 58\u2010year\u2010old male had #18 removed and the extraction socket grafted in the 1980s. In 2016, an implant was placed at #18 and restored with a screw\u2010retained restoration. It developed mobility and was removed in 2017; the explantation site was not grafted. In 2018, another implant was placed at #18 and restored in 2019 with a screw\u2010retained restoration. At the 1\u2010year follow\u2010up, the implant had developed peri\u2010implantitis. Consequently, it was reversed without flap elevation. Four months later, infection remained. A buccal mucoperiosteal flap was reflected. Implant threads remained visible in the grafted bone. During degranulation, an approximately 1\u2010cm3<\/jats:sup> grafted bone specimen dislodged from the mandible. Microscopy of the specimen shows numerous synthetic graft particulates surrounded by vital bone, with a mixed acute and chronic inflammatory infiltrate on its periphery.<\/jats:p><\/jats:sec>Conclusion(s)<\/jats:title>Within the limitation of this case report, absence of bone resorption due to impaired\/altered bone metabolism of the grafted bone likely allowed bacteria to reach and infect the grafted bone via the implant fixture during development and progression of peri\u2010implantitis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cap.10181","type":"journal-article","created":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T15:50:13Z","timestamp":1628524213000},"page":"44-50","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Peri\u2010Implantitis and Concomitant Perigraftitis of an Implant Placed in a Site That Had Alveolar Ridge Preservation Three Decades Earlier: A Case Report With Human Histology"],"prefix":"10.1002","volume":"12","author":[{"given":"Jonathan H.","family":"Do","sequence":"first","affiliation":[{"name":"Section of Periodontics UCLA School of Dentistry Los Angeles California USA"},{"name":"Private Practice Poway California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,8,29]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13057"},{"issue":"4","key":"e_1_2_11_3_1","first-page":"CD010176","article-title":"Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development","volume":"4","author":"Atieh MA","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0588"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1991.tb02319.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2012.02470.x"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2006.01320.x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12491"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1995.tb00143.x"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/cap.10158"}],"container-title":["Clinical Advances in Periodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cap.10181","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cap.10181","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cap.10181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T22:41:16Z","timestamp":1760049676000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1002\/cap.10181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,29]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1002\/cap.10181"],"URL":"https:\/\/doi.org\/10.1002\/cap.10181","archive":["Portico"],"relation":{},"ISSN":["2573-8046","2163-0097"],"issn-type":[{"value":"2573-8046","type":"print"},{"value":"2163-0097","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,29]]},"assertion":[{"value":"2021-04-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}