{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T01:54:24Z","timestamp":1760061264865,"version":"build-2065373602"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T00:00:00Z","timestamp":1636934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>This case reports a biopsy of a large soft tissue defect with gingival grafting. The therapeutic approach presented here combines a partly de\u2010epithelialized free gingival graft (PDFGG) with an envelope technique, which may be useful for cases needing a large reactive lesion biopsy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>A patient with an esthetic and functional complaint due to a fibroepithelial hyperplastic lesion was treated by excisional biopsy leaving a 10 mm cervical defect on tooth 23. A palatal PDFGG was harvested and sutured into the defect, using an \u201cenvelope technique\u201d to improve the blood supply to the graft. The procedure is aimed at both recession coverage and reduction in root hypersensitivity. Stability of the outcome is demonstrated 9 months post\u2010operative.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Gingival margin biopsies pose a significant challenge due to the need to combine significant tissue removal while providing a predictable esthetic and functional outcome. The case is the first description of a successful grafting of a large residual gingival biopsy defect, resulting from using combined mucogingival surgical approach. This technique may be helpful for similar cases.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cap.10187","type":"journal-article","created":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T02:40:59Z","timestamp":1632969659000},"page":"175-179","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Esthetic Mucogingival Treatment After Biopsy of Inflammatory Fibroepithelial Hyperplasia"],"prefix":"10.1002","volume":"12","author":[{"given":"Anat","family":"Katorza","sequence":"first","affiliation":[{"name":"Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Horwitz","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Graduate Dentistry, Rambam Health Care Campus  Haifa Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,11,15]]},"reference":[{"issue":"1","key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.4103\/0300-1652.80074","article-title":"Focal reactive lesions of the gingiva: an analysis of 314 cases at a tertiary health institution in Nigeria","volume":"52","author":"Effiom OA","year":"2011","journal-title":"Niger Med J"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.3889\/oamjms.2017.111"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1590\/1678-775720140122"},{"issue":"5","key":"e_1_2_11_5_1","first-page":"227","article-title":"Pyogenic granuloma, peripheral giant cell granuloma and peripheral ossifying fibroma: retrospective analysis of 138 cases","volume":"57","author":"Salum FG","year":"2008","journal-title":"Minerva Stomatol"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2006.10.018"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.090674"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.19-0350"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13114"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2010.01550.x"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1985.56.7.397"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2017.170105"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01348.x"},{"issue":"5","key":"e_1_2_11_14_1","first-page":"457","article-title":"Covering of gingival recessions with a modified microsurgical tunnel technique: case report","volume":"27","author":"Zuhr O","year":"2007","journal-title":"Int J Periodontics Restorative Dent"},{"issue":"1","key":"e_1_2_11_15_1","first-page":"9","article-title":"Surgical treatment of single gingival recessions: clinical guidelines","volume":"7","author":"Pini\u2010Prato G","year":"2014","journal-title":"Eur J Oral Implantol"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-019-03034-4"}],"container-title":["Clinical Advances in Periodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cap.10187","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cap.10187","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cap.10187","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T21:41:35Z","timestamp":1760046095000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1002\/cap.10187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,15]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["10.1002\/cap.10187"],"URL":"https:\/\/doi.org\/10.1002\/cap.10187","archive":["Portico"],"relation":{},"ISSN":["2573-8046","2163-0097"],"issn-type":[{"type":"print","value":"2573-8046"},{"type":"electronic","value":"2163-0097"}],"subject":[],"published":{"date-parts":[[2021,11,15]]},"assertion":[{"value":"2021-05-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}