{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T15:48:51Z","timestamp":1788536931386,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,6,9]],"date-time":"2022-06-09T00:00:00Z","timestamp":1654732800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Vestibuloplasty is a mucogingival procedure that aims to increase the vestibule and the amount of keratinized tissue (KT) around teeth and dental implants. Currently, the <jats:italic>gold standard<\/jats:italic> in this procedure is still represented by free gingival grafts (FGGs); however, they require a second surgical site, which means more morbidity for the patient and a higher risk of surgical complications, as well as surgical time and chromatic alteration of the recipient area.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>This is a description of the vestibuloplasty technique with platelet\u2010rich fibrin (PRF) in a 35\u2010year\u2010old female patient with a thin gingival phenotype and no medical history of interest. The reason for consultation was tooth sensitivity during brushing and the presence of recessions in the fifth sextant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The use of PRF as a graft biomaterial in vestibuloplasty is a valid and effective option as an alternative to secondary epithelialization of the surgical site, as well as to FGGs, with acceptable results in terms of KT gain and root coverage, and with minimal postoperative discomfort.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key points<\/jats:title><jats:p>Why is this case new information?\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>The use of PRF is an interesting option as an alternative to second\u2010intention healing, as FGGs in vestibuloplasty.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><jats:p>What are the keys to successful management of this case?\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>The most important part of the membranes is the part that was in close relation to the erythrocyte fraction in the blood collection tube, so this part must be oriented toward the recipient bed.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>A minimum of four membranes should be obtained, overlapping one on top of the other.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><jats:p>What are the primary limitations to success in this case?\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>The stability of the PRF.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><\/jats:sec>","DOI":"10.1002\/cap.10201","type":"journal-article","created":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T06:39:05Z","timestamp":1652769545000},"page":"33-37","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["The use of platelet\u2010rich fibrin in vestibuloplasty: A 36\u2010month follow\u2010up technique report"],"prefix":"10.1002","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6534-2816","authenticated-orcid":false,"given":"Angel\u2010Ori\u00f3n","family":"Salgado\u2010Peralvo","sequence":"first","affiliation":[{"name":"Department of Dental Clinical Specialties, Faculty of Dentistry Complutense University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8424-5923","authenticated-orcid":false,"given":"Andrea","family":"Uribarri","sequence":"additional","affiliation":[{"name":"Department of Basic Health Sciences Rey Juan Carlos University  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5162-2841","authenticated-orcid":false,"given":"Naresh","family":"Kewalramani","sequence":"additional","affiliation":[{"name":"Department of Nursery and Stomatology Rey Juan Carlos University  Madrid 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