{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T02:56:52Z","timestamp":1793242612466,"version":"4.5.0"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,6,14]],"date-time":"2022-06-14T00:00:00Z","timestamp":1655164800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Immediate implant in the esthetic area is a challenging procedure. Chronic infection often contributes to extensive bone loss and acute infection often precludes a safe, clean surgery. However, it is quite common to come across failing teeth in the esthetic area, where the patient often demands a faster rehabilitation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>In this clinical case, a fractured upper central incisor was replaced by an immediate implant, and the perimetrical area was filled with heterologous bone blended with patient\u2010derived leukocyte\u2010 and platelet\u2010rich fibrin (L\u2010PRF) in the form of sticky bone. A Maryland bridge was bonded to the adjacent teeth with the intent to guarantee minimum esthetic to the patient. After 5 months, the implant was connected to a definitive abutment and crown. The facial and interdental soft tissue was maintained with appreciable success after 2 years. The pre\u2010treatment and 2\u2010year\u2010 post\u2010treatment computed tomography scans revealed marginal bone preservation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The use of sticky bone and L\u2010PRF in immediate implant sites helps prevent hard and soft\u2010tissue collapse and may favor faster and sounder healing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key points<\/jats:title><jats:p><jats:bold>Why is this case new information?<\/jats:bold>\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>It provides support to the efficacy of immediate implant placement with simultaneous use of L\u2010PRF.<\/jats:p><\/jats:list-item><\/jats:list><\/jats:p><jats:p><jats:bold>What are the keys to successful management of this case?<\/jats:bold>\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Having L\u2010PRF supporting wound healing.<\/jats:p><\/jats:list-item><\/jats:list><\/jats:p><jats:p><jats:bold>What are the primary limitations to success in this case?<\/jats:bold>\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Having sufficient bone apical to the existing socket and at adjacent teeth.<\/jats:p><\/jats:list-item><\/jats:list><\/jats:p><\/jats:sec>","DOI":"10.1002\/cap.10202","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T00:40:03Z","timestamp":1652834403000},"page":"144-148","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Immediate implant and socket preservation using sticky bone and leukocyte\u2010platelet\u2010rich fibrin in the anterior maxilla: A 3\u2010year case report"],"prefix":"10.1002","volume":"13","author":[{"given":"Marco","family":"Cirmeni","sequence":"first","affiliation":[{"name":"Tuscan Stomatological Institute  Camaiore Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ottavio","family":"Fedele","sequence":"additional","affiliation":[{"name":"Tuscan Stomatological Institute  Camaiore Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrica","family":"Giammarinaro","sequence":"additional","affiliation":[{"name":"Tuscan Stomatological Institute  Camaiore Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Marconcini","sequence":"additional","affiliation":[{"name":"Tuscan Stomatological Institute  Camaiore Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugo","family":"Covani","sequence":"additional","affiliation":[{"name":"Tuscan Stomatological Institute  Camaiore Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guerino","family":"Caso","sequence":"additional","affiliation":[{"name":"Tuscan Stomatological Institute  Camaiore 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