{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T01:01:35Z","timestamp":1784682095545,"version":"3.55.0"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T00:00:00Z","timestamp":1742774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T00:00:00Z","timestamp":1742774400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Clin Adv Periodontics"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Vital root resection is a surgical procedure that involves the selective removal of a root of a multi\u2010rooted tooth to preserve the remaining tooth structure and pulp, maintaining the vitality and function of the tooth. When combined with regenerative retrograde vital pulp therapy (rVPT), it may offer a less invasive and more cost\u2010effective alternative to traditional root resection methods. The purpose of this article is to report the techniques and outcomes of vital root resection and rVPT for the periodontally involved fractured mesiobuccal (MB) root in a maxillary first molar.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This case report describes the treatment of a 56\u2010year\u2010old patient with a chief complaint of swelling and pain in her upper right quadrant and with the periodontally involved MB root of tooth #3 using vital root resection combined with rVPT. Tooth #3 was diagnosed as normal pulp and acute periodontal abscess with a suspected root fracture in the MB root. Upon root fracture detection, root resection and rVPT with amnion\u2013chorion membrane and bioceramic material were performed, followed by guided tissue regeneration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Tooth #3 remained asymptomatic with confirmed osseous healing at 6 months, and gingival recession on the adjacent distobuccal root was successfully treated via connective tissue graft. Tooth #3 remained vital at 18 months without clinical and radiographic signs and symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This case report highlights the potential of vital root resection using rVPT as a less invasive treatment modality that may preserve the tooth's vitality and function, offering a cost\u2010effective alternative to more traditional methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>The preservation of tooth function and vitality may be achieved through vital root resection combined with regenerative retrograde vital pulp therapy.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Regenerative retrograde vital pulp therapy may be performed using a bioactive scaffold and bioceramic material.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>This biologically oriented approach may provide a less invasive and more cost\u2010effective alternative to traditional root resection methods that require orthograde endodontic therapy followed by a permanent full\u2010coverage restoration.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Plain language summary<\/jats:title>\n                    <jats:p>This case report presents a minimally invasive dental procedure to preserve tooth function and vitality. A 56\u2010year\u2010old patient reported swelling and pain in the upper right part of her mouth. Examination of tooth #3 revealed an acute gum infection and a likely root fracture in one of the roots. The treatment involved vital root resection, which removes only the damaged root, and regenerative pulp therapy to enhance healing. The regenerative pulp therapy used bioactive materials, including an amnion\u2013chorion membrane and bioceramics, to support tissue regeneration. After 6 months, the patient showed successful bone healing, and gum recession around the treated area was corrected with a connective tissue graft. At the 18\u2010month follow\u2010up, the tooth remained vital and free of symptoms, with no signs of further infection or damage. This case highlights the potential of combining vital root resection and regenerative pulp therapy as a less invasive, cost\u2010effective alternative to traditional methods, allowing the tooth to be preserved while maintaining its natural function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cap.10346","type":"journal-article","created":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T18:11:27Z","timestamp":1742839887000},"page":"153-160","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Vital root resection with regenerative retrograde vital pulp therapy: A case report"],"prefix":"10.1002","volume":"16","author":[{"given":"Yi\u2010Chu","family":"Wu","sequence":"first","affiliation":[{"name":"Division of Periodontics The Ohio State University College of Dentistry  Columbus Ohio USA"},{"name":"Division of Periodontics Columbia University College of Dental Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constance Kang\u2010Ting","family":"Teoh","sequence":"additional","affiliation":[{"name":"Division of Periodontics Columbia University College of Dental Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se Young","family":"Ryoo","sequence":"additional","affiliation":[{"name":"Division of Endodontics Columbia University College of Dental Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Kang","sequence":"additional","affiliation":[{"name":"Division of Periodontics Columbia University College of Dental Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonard","family":"Garfinkel","sequence":"additional","affiliation":[{"name":"Division of Periodontics Columbia University College of Dental Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahng G.","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Endodontics Columbia University College of Dental Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,3,24]]},"reference":[{"issue":"2","key":"e_1_2_9_2_1","first-page":"79","article-title":"Radical and heroic treatment of alveolar abscess by amputation of roots of teeth","volume":"26","author":"Farrar JM","year":"1884","journal-title":"Dental Cosmos"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1954.25.3.213"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13306"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1986.0050"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2011.12.030"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(94)90070-1"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2018.10.003"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(69)90182-0"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(72)90213-7"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(75)80250-0"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2007.tb00525.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/230251"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2021.07.011"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2022.07.012"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41415-020-2590-7"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41415-020-2599-y"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(84)80060-6"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13306"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2013.08.003"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u2010051X.2011.01732.x"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.8.1113"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u2010051X.2012.01918.x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1980.51.4.217"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1976.47.6.324"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.33141"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2014.08.045"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.12140"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2021.04.010"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010019\u201052150\u20104"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/1269534"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2015.01.004"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2018.08.004"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2017.10.012"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13237"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10561\u2010018\u201009743\u20106"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2014.10.018"}],"container-title":["Clinical Advances in Periodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cap.10346","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cap.10346","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cap.10346","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:04:02Z","timestamp":1784678642000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1002\/cap.10346"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,24]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/cap.10346"],"URL":"https:\/\/doi.org\/10.1002\/cap.10346","archive":["Portico"],"relation":{},"ISSN":["2573-8046","2163-0097"],"issn-type":[{"value":"2573-8046","type":"print"},{"value":"2163-0097","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,24]]},"assertion":[{"value":"2024-10-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}